TY - JOUR
T1 - Nanodiscs for the study of membrane proteins
AU - Denisov, Ilia G.
AU - Sligar, Stephen G.
N1 - Publisher Copyright:
© 2024 Elsevier Ltd
PY - 2024/8
Y1 - 2024/8
N2 - Nanodiscs represent a versatile tool for studies of membrane proteins and protein-membrane interactions under native-like conditions. Multiple variations of the Nanodisc platform, as well as new experimental methods, have been recently developed to understand various aspects of structure, dynamics and functional properties of systems involved in signaling, transport, blood coagulation and many other critically important processes. In this mini-review, we focus on some of these exciting recent developments that utilize the Nanodisc platform.
AB - Nanodiscs represent a versatile tool for studies of membrane proteins and protein-membrane interactions under native-like conditions. Multiple variations of the Nanodisc platform, as well as new experimental methods, have been recently developed to understand various aspects of structure, dynamics and functional properties of systems involved in signaling, transport, blood coagulation and many other critically important processes. In this mini-review, we focus on some of these exciting recent developments that utilize the Nanodisc platform.
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U2 - 10.1016/j.sbi.2024.102844
DO - 10.1016/j.sbi.2024.102844
M3 - Review article
C2 - 38795563
AN - SCOPUS:85193863860
SN - 0959-440X
VL - 87
JO - Current Opinion in Structural Biology
JF - Current Opinion in Structural Biology
M1 - 102844
ER -