Nanodiscs for the study of membrane proteins

Ilia G. Denisov, Stephen G. Sligar

Research output: Contribution to journalReview articlepeer-review


Nanodiscs represent a versatile tool for studies of membrane proteins and protein-membrane interactions under native-like conditions. Multiple variations of the Nanodisc platform, as well as new experimental methods, have been recently developed to understand various aspects of structure, dynamics and functional properties of systems involved in signaling, transport, blood coagulation and many other critically important processes. In this mini-review, we focus on some of these exciting recent developments that utilize the Nanodisc platform.

Original languageEnglish (US)
Article number102844
JournalCurrent Opinion in Structural Biology
StatePublished - Aug 2024

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology


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