Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1β production and CD4 T cell activation in autoimmune demyelination

Keyphrases

• Macrophages 100%
• T Cell Activation 100%
• Interleukin-1β 100%
• CD4 T Cells 100%
• Caspase-8 100%
• Pro-inflammatory Interleukins 100%
• Autoimmune Demyelination 100%
• Receptor-interacting Protein Kinase 3 (RIPK3) 100%
• Caspase 60%
• Interleukin 40%
• Multiple Sclerosis 40%
• Microglia 40%
• Experimental Autoimmune Encephalomyelitis 40%
• CASP8 40%
• Granulocyte Colony-stimulating Factor (G-CSF) 20%
• Selective Ablation 20%
• T Cells 20%
• Interferon-α (IFN-α) 20%
• Overproduction 20%
• Receptor-interacting Protein Kinase 1 (RIPK1) 20%
• Regulatory Pathways 20%
• Cell Death 20%
• Myeloid Cells 20%
• Dysregulation 20%
• Genetic Approach 20%
• Mutant Mice 20%
• Functional Links 20%
• Programmed Cell Death 20%
• Cell Inflammation 20%
• Autoimmunity 20%
• Encephalitogenic T Cells 20%
• Active Lesions 20%
• Inflammatory Demyelination 20%
• Immune-mediated Inflammatory Diseases 20%
• NLRP3 Inflammasome 20%
• Autoreactive CD4 T Cells 20%
• Inflammatory Autoimmune Disease 20%

Immunology and Microbiology

• T-Helper Cell 100%
• Interleukin 1 100%
• T Cell Activation 100%
• Myeloid 100%
• Caspase 100%
• Macrophage 62%
• T Cell 25%
• Cytokine 25%
• Cell Death 25%
• Microglia 25%
• Multiple Sclerosis 25%
• Experimental Autoimmune Encephalomyelitis 25%
• interferon 12%
• Granulocyte Macrophage Colony-Stimulating Factor 12%
• Wild Type 12%
• Mouse Mutant 12%
• Autoimmune Disease 12%
• Autoimmunity 12%
• NLRP3 Inflammasome 12%