Abstract
In a continuous effort to emulate the efficiency of biosynthetic pathways, considerable progress has been made in developing one-pot chemoenzymatic processes that take full advantage of the chemo-, regio-, and stereoselectivity of biocatalysts and the productivity of chemical catalysts. Over the last 20 years, research in this area has provided us with proof of concept examples in which chemical and biological transformations occur in one vessel, sequentially or concurrently. These transformations typically access products with high enantiopurity and chemical diversity. In this perspective, we present some of the most successful reports in this field.
Original language | English (US) |
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Pages (from-to) | 2856-2864 |
Number of pages | 9 |
Journal | ACS Catalysis |
Volume | 3 |
Issue number | 12 |
DOIs | |
State | Published - Dec 6 2013 |
Keywords
- artificial metalloenzyme
- biocatalysis
- chemoenzymatic
- dynamic kinetic resolution
- supramolecular assembly
- tandem catalysis
ASJC Scopus subject areas
- Catalysis