Multispectral photoacoustic imaging of tissue denaturation induced by high-intensity focused ultrasound treatment

Yao Sun, King C Li, Brian O'Neill

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents an ex vivo study in imaging high-intensity focused ultrasound induced tissue denaturation with multispectral photoacoustic approach. Beef tissues treated by both water bath and high-intensity focused ultrasound were imaged and evaluated by photoacoustic imaging method, where light in multiple optical wavelengths between 700nm and 900nm is applied. Tissue denaturation after being treated by water bath and high-intensity focused ultrasound has been observed in multispectral photoacoustic images. The denaturation is more striking in relatively shorter optical wavelength photoacoustic images than in relatively longer optical wavelength photoacoustic images. This study suggests that multispectral photoacoustic imaging method is promising in the evaluation of tissue denaturation induced by high- intensity focused ultrasound treatment.

Original languageEnglish (US)
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2013
DOIs
StatePublished - May 28 2013
Externally publishedYes
EventPhotons Plus Ultrasound: Imaging and Sensing 2013 - San Francisco, CA, United States
Duration: Feb 3 2013Feb 5 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8581
ISSN (Print)1605-7422

Other

OtherPhotons Plus Ultrasound: Imaging and Sensing 2013
CountryUnited States
CitySan Francisco, CA
Period2/3/132/5/13

Keywords

  • High-intensity focused ultrasound
  • multispectral photoacoustic imaging
  • thermotherapy
  • tissue denaturation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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