Abstract
We model trabecular bone as a nanocomposite material with hierarchical structure and predict its elastic properties at different structural scales. The analysis involves a bottom-up multi-scale approach, starting with nanoscale (mineralized collagen fibril) and moving up the scales to sub-microscale (single lamella), microscale (single trabecula) and mesoscale (trabecular bone) levels. Continuum micromechanics methods, composite materials laminate theory and finite-element methods are used in the analysis. Good agreement is found between theoretical and experimental results.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1654-1673 |
| Number of pages | 20 |
| Journal | Journal of the Royal Society Interface |
| Volume | 9 |
| Issue number | 72 |
| DOIs | |
| State | Published - Jul 7 2012 |
Keywords
- Elastic moduli
- Hierarchical structure
- MicroCT-based finite-element modelling
- Multi-scale modelling
- Nanocomposite
- Trabecular bone
ASJC Scopus subject areas
- Biophysics
- Biotechnology
- Bioengineering
- Biomedical Engineering
- Biomaterials
- Biochemistry