MRI velocimetry in microchannel networks

L. Guy Raguin, Sharon L. Honecker, John G. Georgiadis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Magnetic Resonance Imaging (MRI) velocimetry was used for the first time to quantify the interstitial 2-1) velocity field of water through un engineered microchannel network constructed from polydimethylsiloxane (PDMS). We describe the fabrication of the multilayered PDMS network, which consists of two identical non-communicating capillary networks, each featuring 2 mm deep and 0.9 mm wide staggered channels forming a 10 × 8 periodic array. The logistics of perfusing the network through multiple interconnects and the velocity extraction are delineated. The effect of a priori or a posteriori methods to estimate the interstitial volume on the accuracy of the pore velocity is shown to be significant.

Original languageEnglish (US)
Title of host publication2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
Pages319-322
Number of pages4
DOIs
StatePublished - Dec 1 2005
Event2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology - Oahu, HI, United States
Duration: May 12 2005May 15 2005

Publication series

Name2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
Volume2005

Other

Other2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
CountryUnited States
CityOahu, HI
Period5/12/055/15/05

Keywords

  • Magnetic resonance imaging
  • Microfluidics
  • Velocimetry

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Raguin, L. G., Honecker, S. L., & Georgiadis, J. G. (2005). MRI velocimetry in microchannel networks. In 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology (pp. 319-322). [1548460] (2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology; Vol. 2005). https://doi.org/10.1109/MMB.2005.1548460