MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals

Liang Cai; Xiaochun Lai; Zengming Shen; Chin Tu Chen; Ling Jian Meng

doi:10.1016/j.nima.2013.08.080

MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals

Liang Cai, Xiaochun Lai, Zengming Shen, Chin Tu Chen, Ling Jian Meng

Research output: Contribution to journal › Article › peer-review

Abstract

In this paper, we will report the development of an ultrahigh resolution MR-compatible SPECT system that can be operated inside a pre-existing clinical MR scanner for simultaneous dual-modality imaging of small animals. This system is constructed with 40 small-pixel CdTe detector modules assembled in a fully stationary ring SPECT geometry. We have experimentally demonstrated that this system is capable of providing an imaging resolution of <500 μm when operating inside MR scanners. We will report the design, construction of the MRI-compatible SPECT system, including the detector technology, collimator, system development and so on. The first imaging results obtained with this newly constructed SPECT system will also be reported.

Original language	English (US)
Pages (from-to)	147-151
Number of pages	5
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	734
Issue number	PART B
DOIs	https://doi.org/10.1016/j.nima.2013.08.080
State	Published - Jan 11 2014

Keywords

CdTe/CZT
Hybrid pixel-waveform readout
MR compatible SPECT
System development

ASJC Scopus subject areas

Nuclear and High Energy Physics
Instrumentation

Online availability

10.1016/j.nima.2013.08.080

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Cai, L., Lai, X., Shen, Z., Chen, C. T., & Meng, L. J. (2014). MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 734(PART B), 147-151. https://doi.org/10.1016/j.nima.2013.08.080

MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals. / Cai, Liang; Lai, Xiaochun; Shen, Zengming et al.
In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 734, No. PART B, 11.01.2014, p. 147-151.

Research output: Contribution to journal › Article › peer-review

Cai, L, Lai, X, Shen, Z, Chen, CT & Meng, LJ 2014, 'MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals', Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 734, no. PART B, pp. 147-151. https://doi.org/10.1016/j.nima.2013.08.080

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MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals

Abstract

Keywords

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