MR diagnosis of pancreatic transplant rejection

T. N. Vahey, G. M. Glazer, I. R. Francis, K. Li, D. C. Dafoe, A. M. Aisen, D. M. Smid

Research output: Contribution to journalArticlepeer-review

Abstract

To determine the role of MR imaging in the assessment of pancreatic transplant rejection, we prospectively obtained 13 MR scans in nine transplant patients. The presence of rejection was verified pathologically by pancreatic biopsies in five patients. In two additional patients, rejection was proved by concordant renal transplant biopsy as well as by compatible clinical and laboratory data. In the remaining two patients, in whom no biopsy was done, clinical and laboratory data showed no evidence of rejection. The mean T2 of the seven pancreata undergoing rejection was significantly elevated (86 msec) compared wtih the mean T2 of the two transplants not undergoing rejection (69 msec) (p < .002). These preliminary results suggest that MR may be useful in the noninvasive diagnosis of pancreatic rejection.

Original languageEnglish (US)
Pages (from-to)557-560
Number of pages4
JournalAmerican Journal of Roentgenology
Volume150
Issue number3
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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