Morphological changes to mouse testicular tissue from in vivo ultrasonic irradiation (preliminary report)

W. D. O'Brien, J. K. Brady, F. Dunn

Research output: Contribution to journalArticlepeer-review


Mouse testes have been ultrasonically irradiated in vivo and subsequently examined morphologically. Each testis was sequentially exposed for 30 sec at a spatial peak intensity of 25 W/cm2 at a frequency of 1 MHz. The testes were removed at varying times post irradiation, from immediate to 19 days, fixed and histologically prepared and stained with hematoxylin and eosin and periodic acid Schiff. The results suggest that two types of ultrasonically induced damage occur wherein, for different specimens under identical exposure conditions, there is either semeniferous tubule disruption with a suggestion of minor intertubule space involvement or a more severe form of tubule damage with significant interstitial tissue involvement. It appears that spermatocytes are affected earlier than spermatogonia, contrary to the situation following ionizing radiation.

Original languageEnglish (US)
Pages (from-to)35-43
Number of pages9
JournalUltrasound in Medicine and Biology
Issue number1
StatePublished - 1979


  • Acoustic
  • Semeniferous tubules
  • Spermatocytes
  • Spermatogonia
  • Testes
  • Ultrasonic damage
  • Ultrasound

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics


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