Morpholino-mediated in vivo silencing of Cryptosporidium parvum lactate dehydrogenase decreases oocyst shedding and infectivity

Keyphrases

• Infectivity 100%
• Parvum 100%
• Lactate Dehydrogenase 100%
• Morpholino 100%
• Cryptosporidium Parvum 100%
• Oocyst Shedding 100%
• In Vivo Gene Silencing 100%
• Cp15 44%
• Knockdown 22%
• Physiological Role 22%
• Oocyst 22%
• Gene Knockout 22%
• Genetic Tools 22%
• Cryptosporidium 22%
• Sporozoite 22%
• Molecular Targets 11%
• Effective Compounds 11%
• Developing Countries 11%
• Interferon-α (IFN-α) 11%
• Knock-in Mouse Model 11%
• Resilience 11%
• Functional Characterization 11%
• Murine Model 11%
• Functional Validation 11%
• Diarrhea 11%
• Lamb 11%
• Calves 11%
• Feces 11%
• Protozoan Parasites 11%
• Toxic Dose 11%
• Child Morbidity 11%
• Diarrheal Disease 11%
• Childhood Mortality 11%
• Goat Kids 11%

Biochemistry, Genetics and Molecular Biology

• Lactate Dehydrogenase 100%
• Morpholino 100%
• Cryptosporidium parvum 100%
• Oocyst 100%
• Genetics 33%
• Gene Knockdown 33%
• Sporozoite 33%
• Cryptosporidium 33%
• Knockout Mouse 16%
• Protozoon 16%
• Essential Gene 16%
• Lamb 16%
• Toxic Dose 16%
• Kid (Goat) 16%
• Interferon 16%

Immunology and Microbiology

• Cryptosporidium parvum 100%
• Oocyst 100%
• Gene Knockdown 50%
• Cryptosporidium 50%
• Sporozoite 50%
• Feces 25%
• interferon 25%
• Knockout Mouse 25%
• Protozoa 25%
• Essential Gene 25%
• Lamb 25%
• Toxic Dose 25%
• Kid (Goat) 25%