Monte Carlo Calculation of Rectal Dose When Using an Intrarectal Balloon During Prostate Radiation Therapy

Jun S. Song; Laurence E. Court; Robert A. Cormack

doi:10.1016/j.meddos.2006.11.002

Monte Carlo Calculation of Rectal Dose When Using an Intrarectal Balloon During Prostate Radiation Therapy

Jun S. Song, Laurence E. Court, Robert A. Cormack

Research output: Contribution to journal › Article › peer-review

Abstract

Air-filled intrarectal balloons can be used to localize and immobilize the prostate for radiation therapy, allowing dose escalation to the prostate and reducing the probability of radiation proctitis, but also introducing potentially significant heterogeneity. We compare the Eclipse treatment planning system (TPS) with Monte Carlo (MC) simulations for 5 patients to assess how well a conventional TPS includes the effect of the balloon on doses near the rectum. The MC results show that, for a 27-Gy prescription to the 95% isodose line, Eclipse overestimates the volume of the rectum receiving more than 26 Gy (96%) by 2∼10 cc and the volume of the rectum receiving between 12∼15 Gy by 10∼20 cc. Differential dose volume histograms are also computed and compared for individual fields in the anterior expansion of the rectum, and the TPS is again shown to predict higher mean dose in the region by 0.3∼1.0 Gy.

Original language	English (US)
Pages (from-to)	151-156
Number of pages	6
Journal	Medical Dosimetry
Volume	32
Issue number	3
DOIs	https://doi.org/10.1016/j.meddos.2006.11.002
State	Published - Sep 2007
Externally published	Yes

Keywords

Balloon
DVH
Monte Carlo
Prostate cancer

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
General Health Professions
Radiation

Online availability

10.1016/j.meddos.2006.11.002

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title = "Monte Carlo Calculation of Rectal Dose When Using an Intrarectal Balloon During Prostate Radiation Therapy",

abstract = "Air-filled intrarectal balloons can be used to localize and immobilize the prostate for radiation therapy, allowing dose escalation to the prostate and reducing the probability of radiation proctitis, but also introducing potentially significant heterogeneity. We compare the Eclipse treatment planning system (TPS) with Monte Carlo (MC) simulations for 5 patients to assess how well a conventional TPS includes the effect of the balloon on doses near the rectum. The MC results show that, for a 27-Gy prescription to the 95% isodose line, Eclipse overestimates the volume of the rectum receiving more than 26 Gy (96%) by 2∼10 cc and the volume of the rectum receiving between 12∼15 Gy by 10∼20 cc. Differential dose volume histograms are also computed and compared for individual fields in the anterior expansion of the rectum, and the TPS is again shown to predict higher mean dose in the region by 0.3∼1.0 Gy.",

keywords = "Balloon, DVH, Monte Carlo, Prostate cancer",

author = "Song, {Jun S.} and Court, {Laurence E.} and Cormack, {Robert A.}",

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AU - Song, Jun S.

AU - Court, Laurence E.

AU - Cormack, Robert A.

PY - 2007/9

Y1 - 2007/9

N2 - Air-filled intrarectal balloons can be used to localize and immobilize the prostate for radiation therapy, allowing dose escalation to the prostate and reducing the probability of radiation proctitis, but also introducing potentially significant heterogeneity. We compare the Eclipse treatment planning system (TPS) with Monte Carlo (MC) simulations for 5 patients to assess how well a conventional TPS includes the effect of the balloon on doses near the rectum. The MC results show that, for a 27-Gy prescription to the 95% isodose line, Eclipse overestimates the volume of the rectum receiving more than 26 Gy (96%) by 2∼10 cc and the volume of the rectum receiving between 12∼15 Gy by 10∼20 cc. Differential dose volume histograms are also computed and compared for individual fields in the anterior expansion of the rectum, and the TPS is again shown to predict higher mean dose in the region by 0.3∼1.0 Gy.

AB - Air-filled intrarectal balloons can be used to localize and immobilize the prostate for radiation therapy, allowing dose escalation to the prostate and reducing the probability of radiation proctitis, but also introducing potentially significant heterogeneity. We compare the Eclipse treatment planning system (TPS) with Monte Carlo (MC) simulations for 5 patients to assess how well a conventional TPS includes the effect of the balloon on doses near the rectum. The MC results show that, for a 27-Gy prescription to the 95% isodose line, Eclipse overestimates the volume of the rectum receiving more than 26 Gy (96%) by 2∼10 cc and the volume of the rectum receiving between 12∼15 Gy by 10∼20 cc. Differential dose volume histograms are also computed and compared for individual fields in the anterior expansion of the rectum, and the TPS is again shown to predict higher mean dose in the region by 0.3∼1.0 Gy.

KW - Balloon

KW - DVH

KW - Monte Carlo

KW - Prostate cancer

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Monte Carlo Calculation of Rectal Dose When Using an Intrarectal Balloon During Prostate Radiation Therapy

Abstract

Keywords

ASJC Scopus subject areas

Online availability

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