Abstract
The title compound, Na+·C5H9N2O7P 2-·4H2O, is an isomer of zoledronate, a potent bone antiresorptive bisphosphonate drug having significant activity against several parasitic protozoa. The crystal structure of isozoledronate consists of bisphosphonate dimers coordinated by two Na+ ions. The dimers are held together through an extensive hydrogen-bonding network. The crystals exhibit non-merohedral twinning that roughly superimposes the a and b axes, and inverts the c axis.
Original language | English (US) |
---|---|
Pages (from-to) | m599-m600 |
Journal | Acta Crystallographica Section C: Crystal Structure Communications |
Volume | 58 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2002 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology