Monitoring neuropeptides in cellular releasate by electrospray ionization mass spectrometry

Jennifer A. Jakubowski, Wayne P. Kelley, Stanislav Rubakhin, Brian R. Monroe, Jonathan V Sweedler

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The neuropeptides in cellular releasate were monitored by using electrospray ionization mass spectrometry. Neuropeptides play a vital role in determining the activity of neural network to understand the neuropeptide releases. Additional studies with peptide standards in artificial seawater were performed in order to assess the effectiveness of an offline solid-phase extraction (SPE) procedure. It was observed that the salt-removal process was necessary for neuropeptide detection in ESI-Ion trap-MS.

Original languageEnglish (US)
Title of host publicationProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Pages369-370
Number of pages2
StatePublished - 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002

Other

OtherProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
CountryUnited States
CityOrlando, FL
Period6/2/026/6/02

ASJC Scopus subject areas

  • Spectroscopy

Fingerprint Dive into the research topics of 'Monitoring neuropeptides in cellular releasate by electrospray ionization mass spectrometry'. Together they form a unique fingerprint.

Cite this