TY - JOUR
T1 - Molecular profiling of single cells and tissue specimens with quantum dots
AU - Gao, Xiaohu
AU - Nie, Shuming
N1 - Funding Information:
The authors are grateful to Dominic Ansari and Dr. Zhongxing Liang for technical help, and to Professors Leland Chung, Fray Marshall, John Petros, Hyunsuk Shim, Jonathan Simons, and Lily Yang for stimulating discussions on cancer research. They also acknowledge financial support from the National Institute of Health (R01 GM60562) and the Coulter Translational Research Program at Georgia Tech and Emory University.
PY - 2003/9/1
Y1 - 2003/9/1
N2 - Quantum dots are tiny light-emitting particles on the nanometer scale. They are emerging as a new class of biological label with properties and applications that are not available with traditional organic dyes and fluorescent proteins. Recent advances, as reported in Science and Nature Biotechnology, have led to quantum dot bioconjugates that are highly luminescent and stable. These bioconjugates raise new possibilities for studying genes, proteins and drug targets in single cells, tissue specimens and even in living animals.
AB - Quantum dots are tiny light-emitting particles on the nanometer scale. They are emerging as a new class of biological label with properties and applications that are not available with traditional organic dyes and fluorescent proteins. Recent advances, as reported in Science and Nature Biotechnology, have led to quantum dot bioconjugates that are highly luminescent and stable. These bioconjugates raise new possibilities for studying genes, proteins and drug targets in single cells, tissue specimens and even in living animals.
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U2 - 10.1016/S0167-7799(03)00209-9
DO - 10.1016/S0167-7799(03)00209-9
M3 - Short survey
C2 - 12948664
AN - SCOPUS:0041424802
SN - 0167-7799
VL - 21
SP - 371
EP - 373
JO - Trends in Biotechnology
JF - Trends in Biotechnology
IS - 9
ER -