Abstract
This review highlights recent surface force measurements of the molecular interactions of protein adhesives. These studies identified novel molecular-binding mechanisms that are intimately linked to the protein structures. Central to these findings is the precise force and distance sensitivity achieved with the surface force apparatus. They illustrate that a mechanistic understanding of the nanomechanical properties of biomolecular adhesives requires measurements of both the strength of adhesion and the range of the protein interactions.
Original language | English (US) |
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Pages (from-to) | 409-432 |
Number of pages | 24 |
Journal | Journal of Adhesion |
Volume | 80 |
Issue number | 5 |
DOIs | |
State | Published - May 2004 |
Keywords
- Cadherin
- CD2
- Cell adhesion
- NCAM
- Polysialic acid
- Surface force apparatus
ASJC Scopus subject areas
- Chemical Engineering(all)
- Materials Science(all)
- Mechanics of Materials
- Computational Mechanics