Molecular Imaging and Nanotechnology—Emerging Tools in Diagnostics and Therapy

Marcin Woźniak, Agata Płoska, Anna Siekierzycka, Lawrence W. Dobrucki, Leszek Kalinowski, Iwona T. Dobrucki

Research output: Contribution to journalReview articlepeer-review

Abstract

Personalized medicine is emerging as a new goal in the diagnosis and treatment of diseases. This approach aims to establish differences between patients suffering from the same disease, which allows to choose the most effective treatment. Molecular imaging (MI) enables advanced insight into molecule interactions and disease pathology, improving the process of diagnosis and therapy and, for that reason, plays a crucial role in personalized medicine. Nanoparticles are widely used in MI techniques due to their size, high surface area to volume ratio, and multifunctional properties. After conjugation to specific ligands and drugs, nanoparticles can transport therapeutic compounds directly to their area of action and therefore may be used in theranostics—the simultaneous imple-mentation of treatment and diagnostics. This review summarizes different MI techniques, including optical imaging, ultrasound imaging, magnetic resonance imaging, nuclear imaging, and computed tomography imaging with theranostics nanoparticles. Furthermore, it explores the potential use of constructs that enables multimodal imaging and track diseases in real time.

Original languageEnglish (US)
Article number2658
JournalInternational journal of molecular sciences
Volume23
Issue number5
DOIs
StatePublished - Mar 1 2022

Keywords

  • Imaging modalities
  • Molecular imaging
  • Nanoparticles
  • Nanotechnology
  • Personalized medicine
  • Theranostics

ASJC Scopus subject areas

  • Molecular Biology
  • Spectroscopy
  • Catalysis
  • Inorganic Chemistry
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Molecular Imaging and Nanotechnology—Emerging Tools in Diagnostics and Therapy'. Together they form a unique fingerprint.

Cite this