Molecular evolution of the major arthropod chemoreceptor gene families

Research output: Contribution to journalReview article

Abstract

The evolutionary origins of the three major families of chemoreceptors in arthropods-the odorant receptor (OR), gustatory receptor (GR), and ionotropic receptor (IR) families-occurred at the base of the Insecta, Animalia, and Protostomia, respectively. Comparison of receptor family sizes across arthropods reveals a generally positive correlation with their widely disparate complexity of chemical ecology. Closely related species reveal the ongoing processes of gene family evolution, including gene duplication, divergence, pseudogenization, and loss, that mediate these larger patterns. Sets of paralogous receptors within species reveal positive selection on amino acids in regions likely to contribute to ligand binding and specificity. Ligands of many ORs and some GRs and IRs have been identified; however, ligand identification for many more chemoreceptors is needed, as are structures for the OR/GR superfamily, to improve our understanding of the molecular evolution of these ecologically important receptors in arthropods.

Original languageEnglish (US)
Pages (from-to)227-242
Number of pages16
JournalAnnual Review of Entomology
Volume64
DOIs
StatePublished - Jan 7 2019

Fingerprint

chemoreceptors
arthropod
arthropods
ligand
receptors
gene
genes
chemical ecology
family size
Animalia
gene duplication
Insecta
amino acid
divergence
amino acids
family
ligands
taste receptors
odorant receptors

Keywords

  • Gustatory receptor
  • Ionotropic receptor
  • Odorant receptor
  • Positive selection

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Insect Science

Cite this

Molecular evolution of the major arthropod chemoreceptor gene families. / Robertson, Hugh M.

In: Annual Review of Entomology, Vol. 64, 07.01.2019, p. 227-242.

Research output: Contribution to journalReview article

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