Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007

Ying chun Dai, Gui fang Hu, Xu fu Zhang, Can lei Song, Wen long Xiang, Xian bo Wu, Le yi Wang, Xi Jiang, Jun Nie

Research output: Contribution to journalArticlepeer-review

Abstract

Human noroviruses (NoVs) are an important cause of epidemic acute gastroenteritis. Their role in sporadic cases, however, is less clear. In this study, we performed a two-year surveillance (September 2005 to August 2007) of NoV gastroenteritis in outpatient clinics in a southern city of China, Jiangmen City. NoVs were detected in 115 patients (115/881, 13. 1%) with 30 (26. 1%) co-infections with rotaviruses. Sequence analysis showed that all 115 NoVs belonged to genogroup II, with GII. 4 being the most predominant (87. 8%). NoV-associated infection can be seen year-around, with autumn and winter peaks. This study provides basic information on sporadic cases of major NoV gastroenteritis in children in different seasons, which is valuable for future disease control and prevention.

Original languageEnglish (US)
Pages (from-to)1641-1646
Number of pages6
JournalArchives of Virology
Volume156
Issue number9
DOIs
StatePublished - Sep 2011
Externally publishedYes

Keywords

  • Acute gastroenteritis
  • Calicivirus
  • Diarrhea
  • Norovirus
  • Recombinant
  • Sporadic cases

ASJC Scopus subject areas

  • Virology

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