Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007

Ying chun Dai; Gui fang Hu; Xu fu Zhang; Can lei Song; Wen long Xiang; Xian bo Wu; Le yi Wang; Xi Jiang; Jun Nie

doi:10.1007/s00705-011-1010-3

Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007

Ying chun Dai, Gui fang Hu, Xu fu Zhang, Can lei Song, Wen long Xiang, Xian bo Wu, Le yi Wang, Xi Jiang, Jun Nie

Research output: Contribution to journal › Article › peer-review

Abstract

Human noroviruses (NoVs) are an important cause of epidemic acute gastroenteritis. Their role in sporadic cases, however, is less clear. In this study, we performed a two-year surveillance (September 2005 to August 2007) of NoV gastroenteritis in outpatient clinics in a southern city of China, Jiangmen City. NoVs were detected in 115 patients (115/881, 13. 1%) with 30 (26. 1%) co-infections with rotaviruses. Sequence analysis showed that all 115 NoVs belonged to genogroup II, with GII. 4 being the most predominant (87. 8%). NoV-associated infection can be seen year-around, with autumn and winter peaks. This study provides basic information on sporadic cases of major NoV gastroenteritis in children in different seasons, which is valuable for future disease control and prevention.

Original language	English (US)
Pages (from-to)	1641-1646
Number of pages	6
Journal	Archives of Virology
Volume	156
Issue number	9
DOIs	https://doi.org/10.1007/s00705-011-1010-3
State	Published - Sep 2011
Externally published	Yes

Keywords

Acute gastroenteritis
Calicivirus
Diarrhea
Norovirus
Recombinant
Sporadic cases

ASJC Scopus subject areas

Virology

Online availability

10.1007/s00705-011-1010-3

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title = "Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007",

abstract = "Human noroviruses (NoVs) are an important cause of epidemic acute gastroenteritis. Their role in sporadic cases, however, is less clear. In this study, we performed a two-year surveillance (September 2005 to August 2007) of NoV gastroenteritis in outpatient clinics in a southern city of China, Jiangmen City. NoVs were detected in 115 patients (115/881, 13. 1%) with 30 (26. 1%) co-infections with rotaviruses. Sequence analysis showed that all 115 NoVs belonged to genogroup II, with GII. 4 being the most predominant (87. 8%). NoV-associated infection can be seen year-around, with autumn and winter peaks. This study provides basic information on sporadic cases of major NoV gastroenteritis in children in different seasons, which is valuable for future disease control and prevention.",

keywords = "Acute gastroenteritis, Calicivirus, Diarrhea, Norovirus, Recombinant, Sporadic cases",

author = "Dai, {Ying chun} and Hu, {Gui fang} and Zhang, {Xu fu} and Song, {Can lei} and Xiang, {Wen long} and Wu, {Xian bo} and Wang, {Le yi} and Xi Jiang and Jun Nie",

note = "Funding Information: The authors are grateful to CDC of Jiangmen city for the specimens and data collection. This study was supported by the National Natural Science Foundation of China (Grants 30700716 and 30901992), Medical Scientific Research Foundation of Guangdong Province (B2010174), Doctoral Fund of Ministry of Education of China (No. 20104433120015), and Guangdong Province “211 Project” (Grant No. GW201006 and GW201106) of Southern Medical University. Dr. Jiang was supported by the NIH of the United States (R01 AI37093 and R01 AI55649). ",

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doi = "10.1007/s00705-011-1010-3",

language = "English (US)",

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T1 - Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007

AU - Dai, Ying chun

AU - Hu, Gui fang

AU - Zhang, Xu fu

AU - Song, Can lei

AU - Xiang, Wen long

AU - Wu, Xian bo

AU - Wang, Le yi

AU - Jiang, Xi

AU - Nie, Jun

N1 - Funding Information: The authors are grateful to CDC of Jiangmen city for the specimens and data collection. This study was supported by the National Natural Science Foundation of China (Grants 30700716 and 30901992), Medical Scientific Research Foundation of Guangdong Province (B2010174), Doctoral Fund of Ministry of Education of China (No. 20104433120015), and Guangdong Province “211 Project” (Grant No. GW201006 and GW201106) of Southern Medical University. Dr. Jiang was supported by the NIH of the United States (R01 AI37093 and R01 AI55649).

PY - 2011/9

Y1 - 2011/9

N2 - Human noroviruses (NoVs) are an important cause of epidemic acute gastroenteritis. Their role in sporadic cases, however, is less clear. In this study, we performed a two-year surveillance (September 2005 to August 2007) of NoV gastroenteritis in outpatient clinics in a southern city of China, Jiangmen City. NoVs were detected in 115 patients (115/881, 13. 1%) with 30 (26. 1%) co-infections with rotaviruses. Sequence analysis showed that all 115 NoVs belonged to genogroup II, with GII. 4 being the most predominant (87. 8%). NoV-associated infection can be seen year-around, with autumn and winter peaks. This study provides basic information on sporadic cases of major NoV gastroenteritis in children in different seasons, which is valuable for future disease control and prevention.

AB - Human noroviruses (NoVs) are an important cause of epidemic acute gastroenteritis. Their role in sporadic cases, however, is less clear. In this study, we performed a two-year surveillance (September 2005 to August 2007) of NoV gastroenteritis in outpatient clinics in a southern city of China, Jiangmen City. NoVs were detected in 115 patients (115/881, 13. 1%) with 30 (26. 1%) co-infections with rotaviruses. Sequence analysis showed that all 115 NoVs belonged to genogroup II, with GII. 4 being the most predominant (87. 8%). NoV-associated infection can be seen year-around, with autumn and winter peaks. This study provides basic information on sporadic cases of major NoV gastroenteritis in children in different seasons, which is valuable for future disease control and prevention.

KW - Acute gastroenteritis

KW - Calicivirus

KW - Diarrhea

KW - Norovirus

KW - Recombinant

KW - Sporadic cases

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Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007

Abstract

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