Molecular Clock

M. Wang; G. Caetano-Anollés

doi:10.1016/B978-0-12-374984-0.00964-5

Molecular Clock

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The hypothesis of the molecular clock posits that the rate of evolution of a macromolecule is approximately constant over time and among different evolutionary lineages. Despite provoking many controversies since it was put forth in the early 1960s, the molecular clock has had remarkable influence on today's theories of molecular evolution and has inspired a number of tools for constructing evolutionary timescales.

Original language	English (US)
Title of host publication	Brenner's Encyclopedia of Genetics
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	461-462
Number of pages	2
ISBN (Electronic)	9780080961569
ISBN (Print)	9780123749840
DOIs	https://doi.org/10.1016/B978-0-12-374984-0.00964-5
State	Published - Feb 27 2013

Keywords

Divergence
Evolutionary rate
Global clock
Local clock
Neutral theory
Phylogenetic tree
Relative-rate test
Species

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology
General Medicine

Online availability

10.1016/B978-0-12-374984-0.00964-5

Library availability

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Cite this

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AU - Caetano-Anollés, G.

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AB - The hypothesis of the molecular clock posits that the rate of evolution of a macromolecule is approximately constant over time and among different evolutionary lineages. Despite provoking many controversies since it was put forth in the early 1960s, the molecular clock has had remarkable influence on today's theories of molecular evolution and has inspired a number of tools for constructing evolutionary timescales.

KW - Divergence

KW - Evolutionary rate

KW - Global clock

KW - Local clock

KW - Neutral theory

KW - Phylogenetic tree

KW - Relative-rate test

KW - Species

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BT - Brenner's Encyclopedia of Genetics

PB - Elsevier Inc.

ER -

Molecular Clock

Abstract

Keywords

ASJC Scopus subject areas

Online availability

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