Molecular and structural analysis of viscoelastic properties

Rebecca D. Yapp, Sureshkumar Kalyanam, Michael F. Insana

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Elasticity imaging is emerging as an important tool for breast cancer detection and monitoring of treatment. Viscoelastic image contrast in breast lesions is generated by disease specific processes that modify the molecular structure of connective tissues. We showed previously that gelatin hydrogels exhibit mechanical behavior similar to native collagen found in breast tissue and therefore are suitable as phantoms for elasticity imaging. This paper summarizes our study of the viscoelastic properties of hydrogels designed to discover molecular-scale sources of elasticity image contrast.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2007
Subtitle of host publicationPhysiology, Function, and Structure from Medical Images
EditionPART 2
DOIs
StatePublished - Oct 15 2007
EventMedical Imaging 2007: Physiology, Function, and Structure from Medical Images - San Diego, CA, United States
Duration: Feb 18 2007Feb 20 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
NumberPART 2
Volume6511
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2007: Physiology, Function, and Structure from Medical Images
CountryUnited States
CitySan Diego, CA
Period2/18/072/20/07

Keywords

  • Breast cancer
  • Elasticity imaging
  • Polymer mechanics
  • Ultrasound

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Yapp, R. D., Kalyanam, S., & Insana, M. F. (2007). Molecular and structural analysis of viscoelastic properties. In Medical Imaging 2007: Physiology, Function, and Structure from Medical Images (PART 2 ed.). [65111Y] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6511, No. PART 2). https://doi.org/10.1117/12.708723