Modulation of DNA constraints that control macromolecular folding

Chandrasekhar V. Miduturu, Scott K Silverman

Research output: Contribution to journalArticle

Abstract

(Figure Presented) Taking control with DNA: Covalently attached double-stranded DNA constraints can control the conformations of other macromolecules. A variety of approaches (including competitive ligand-aptamer interactions) were used to modulate the effects of such constraints on the structure of a large RNA molecule.

Original languageEnglish (US)
Pages (from-to)1918-1921
Number of pages4
JournalAngewandte Chemie - International Edition
Volume45
Issue number12
DOIs
StatePublished - Mar 13 2006

Fingerprint

DNA
Modulation
RNA
Macromolecules
Conformations
Ligands
Molecules

Keywords

  • Aptamers
  • DNA
  • Nanotechnology
  • RNA
  • Structural constraints

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Modulation of DNA constraints that control macromolecular folding. / Miduturu, Chandrasekhar V.; Silverman, Scott K.

In: Angewandte Chemie - International Edition, Vol. 45, No. 12, 13.03.2006, p. 1918-1921.

Research output: Contribution to journalArticle

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