Modulation of DNA constraints that control macromolecular folding

Chandrasekhar V. Miduturu, Scott K. Silverman

Research output: Contribution to journalArticlepeer-review


(Figure Presented) Taking control with DNA: Covalently attached double-stranded DNA constraints can control the conformations of other macromolecules. A variety of approaches (including competitive ligand-aptamer interactions) were used to modulate the effects of such constraints on the structure of a large RNA molecule.

Original languageEnglish (US)
Pages (from-to)1918-1921
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number12
StatePublished - Mar 13 2006


  • Aptamers
  • DNA
  • Nanotechnology
  • RNA
  • Structural constraints

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry


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