Modified hydrogenase for producing hydrogen

Klaus Schulten

Research output: Contribution to journalArticlepeer-review


A team of researchers at the University of Illinois and the US DOE created a model of the hydrogenase CpI molecule from Clostridium pasteurianum so they could visualize how the oxygen and hydrogen diffuse from the solution outside the enzyme into the active site within the protein molecule. The group discovered that since the oxygen molecule is larger than the hydrogen molecule, it moves through a few localized, fluctuating channels. Hydrogen, being smaller, moves more freely through the protein, traveling both through the pathways oxygen uses as well as other paths too narrow for oxygen to pass.

Original languageEnglish
Pages (from-to)4-5
Number of pages2
JournalIndustrial Bioprocessing
Issue number11
StatePublished - Nov 2005

ASJC Scopus subject areas

  • Energy (miscellaneous)


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