TY - GEN
T1 - Model-based MR parameter mapping with sparsity constraint
AU - Zhao, Bo
AU - Lam, Fan
AU - Lu, Wenmiao
AU - Liang, Zhi Pei
PY - 2013
Y1 - 2013
N2 - MR parameter mapping (e.g., T1 mapping, T2 mapping, or T2* mapping) is a valuable tool for tissue characterization. However, its practical utility has been limited due to long data acquisition time. This paper addresses this problem with a new model-based parameter mapping method, which utilizes an explicit signal model and imposes a sparsity constraint on the parameter values. The proposed method enables direct estimation of the parameters of interest from highly undersampled, noisy k-space data. An algorithm is presented to solve the underlying parameter estimation problem. Its performance is analyzed using estimation-theoretic bounds. Some representative results from T2 brain mapping are also presented to illustrate the performance of the proposed method for accelerating parameter mapping.
AB - MR parameter mapping (e.g., T1 mapping, T2 mapping, or T2* mapping) is a valuable tool for tissue characterization. However, its practical utility has been limited due to long data acquisition time. This paper addresses this problem with a new model-based parameter mapping method, which utilizes an explicit signal model and imposes a sparsity constraint on the parameter values. The proposed method enables direct estimation of the parameters of interest from highly undersampled, noisy k-space data. An algorithm is presented to solve the underlying parameter estimation problem. Its performance is analyzed using estimation-theoretic bounds. Some representative results from T2 brain mapping are also presented to illustrate the performance of the proposed method for accelerating parameter mapping.
KW - model-based reconstruction
KW - parameter estimation
KW - parameter mapping
KW - sparsity
UR - http://www.scopus.com/inward/record.url?scp=84881656094&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84881656094&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2013.6556397
DO - 10.1109/ISBI.2013.6556397
M3 - Conference contribution
AN - SCOPUS:84881656094
SN - 9781467364546
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 1
EP - 4
BT - ISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging
T2 - 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013
Y2 - 7 April 2013 through 11 April 2013
ER -