Mitigating artifacts via half-time reconstruction in thermoacoustic tomography

Mark A. Anastasio, Jin Zhang, Xiaochuan Pan, Geng Ku, Lihong V. Wang

Research output: Contribution to journalConference articlepeer-review


Thermoacoustic tomography (TAT) is an ultrasound-mediated biophotonic imaging modality with great potential for a wide range of biomedical imaging applications. In this work, we demonstrate that half-time reconstruction approaches for TAT can mitigate image artifacts due to heterogeneous acoustic properties of an object. We also discuss how half-time reconstruction approaches permit explicit control of statistically complementary information in the measurement data, which can facilitate the reduction of image variances.

Original languageEnglish (US)
Article number41
Pages (from-to)263-270
Number of pages8
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
StatePublished - 2005
Externally publishedYes
EventSixth Conference on Biomedical Thermosacoustics, Optoacoustics, and Acousto-Optics - Photons Plus Ultrasound: Imaging and Sensing 2005 - San Jose, CA, United States
Duration: Jan 23 2005Jan 25 2005


  • Generalized Radon transform
  • Image reconstruction
  • Photoacoustic tomography
  • Thermoacoustic tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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