Minimum Information about a Biosynthetic Gene cluster

Marnix H. Medema, Renzo Kottmann, Pelin Yilmaz, Matthew Cummings, John B. Biggins, Kai Blin, Irene De Bruijn, Yit Heng Chooi, Jan Claesen, R. Cameron Coates, Pablo Cruz-Morales, Srikanth Duddela, Stephanie Düsterhus, Daniel J. Edwards, David P. Fewer, Neha Garg, Christoph Geiger, Juan Pablo Gomez-Escribano, Anja Greule, Michalis HadjithomasAnthony S. Haines, Eric J.N. Helfrich, Matthew L. Hillwig, Keishi Ishida, Adam C. Jones, Carla S. Jones, Katrin Jungmann, Carsten Kegler, Hyun Uk Kim, Peter Kötter, Daniel Krug, Joleen Masschelein, Alexey V. Melnik, Simone M. Mantovani, Emily A. Monroe, Marcus Moore, Nathan Moss, Hans Wilhelm Nützmann, Guohui Pan, Amrita Pati, Daniel Petras, F. Jerry Reen, Federico Rosconi, Zhe Rui, Zhenhua Tian, Nicholas J. Tobias, Yuta Tsunematsu, Philipp Wiemann, Elizabeth Wyckoff, Xiaohui Yan, Grace Yim, Fengan Yu, Yunchang Xie, Bertrand Aigle, Alexander K. Apel, Carl J. Balibar, Emily P. Balskus, Francisco Barona-Gómez, Andreas Bechthold, Helge B. Bode, Rainer Borriss, Sean F. Brady, Axel A. Brakhage, Patrick Caffrey, Yi Qiang Cheng, Jon Clardy, Russell J. Cox, René De Mot, Stefano Donadio, Mohamed S. Donia, Wilfred A. Van Der Donk, Pieter C. Dorrestein, Sean Doyle, Arnold J.M. Driessen, Monika Ehling-Schulz, Karl Dieter Entian, Michael A. Fischbach, Lena Gerwick, William H. Gerwick, Harald Gross, Bertolt Gust, Christian Hertweck, Monica Höfte, Susan E. Jensen, Jianhua Ju, Leonard Katz, Leonard Kaysser, Jonathan L. Klassen, Nancy P. Keller, Jan Kormanec, Oscar P. Kuipers, Tomohisa Kuzuyama, Nikos C. Kyrpides, Hyung Jin Kwon, Sylvie Lautru, Rob Lavigne, Chia Y. Lee, Bai Linquan, Xinyu Liu, Wen Liu, Andriy Luzhetskyy, Taifo Mahmud, Yvonne Mast, Carmen Méndez, Mikko Metsä-Ketelä, Jason Micklefield, Douglas A. Mitchell, Bradley S. Moore, Leonilde M. Moreira, Rolf Müller, Brett A. Neilan, Markus Nett, Jens Nielsen, Fergal O'Gara, Hideaki Oikawa, Anne Osbourn, Marcia S. Osburne, Bohdan Ostash, Shelley M. Payne, Jean Luc Pernodet, Miroslav Petricek, Jörn Piel, Olivier Ploux, Jos M. Raaijmakers, José A. Salas, Esther K. Schmitt, Barry Scott, Ryan F. Seipke, Ben Shen, David H. Sherman, Kaarina Sivonen, Michael J. Smanski, Margherita Sosio, Evi Stegmann, Roderich D. Süssmuth, Kapil Tahlan, Christopher M. Thomas, Yi Tang, Andrew W. Truman, Muriel Viaud, Jonathan D. Walton, Christopher T. Walsh, Tilmann Weber, Gilles P. Van Wezel, Barrie Wilkinson, Joanne M. Willey, Wolfgang Wohlleben, Gerard D. Wright, Nadine Ziemert, Changsheng Zhang, Sergey B. Zotchev, Rainer Breitling, Eriko Takano, Frank Oliver Glöckner

Research output: Contribution to journalReview article

Abstract

A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

Original languageEnglish (US)
Pages (from-to)625-631
Number of pages7
JournalNature chemical biology
Volume11
Issue number9
DOIs
StatePublished - Aug 18 2015

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Multigene Family
Information Storage and Retrieval
Fungi
Bacteria

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Cite this

Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., ... Glöckner, F. O. (2015). Minimum Information about a Biosynthetic Gene cluster. Nature chemical biology, 11(9), 625-631. https://doi.org/10.1038/nchembio.1890

Minimum Information about a Biosynthetic Gene cluster. / Medema, Marnix H.; Kottmann, Renzo; Yilmaz, Pelin; Cummings, Matthew; Biggins, John B.; Blin, Kai; De Bruijn, Irene; Chooi, Yit Heng; Claesen, Jan; Coates, R. Cameron; Cruz-Morales, Pablo; Duddela, Srikanth; Düsterhus, Stephanie; Edwards, Daniel J.; Fewer, David P.; Garg, Neha; Geiger, Christoph; Gomez-Escribano, Juan Pablo; Greule, Anja; Hadjithomas, Michalis; Haines, Anthony S.; Helfrich, Eric J.N.; Hillwig, Matthew L.; Ishida, Keishi; Jones, Adam C.; Jones, Carla S.; Jungmann, Katrin; Kegler, Carsten; Kim, Hyun Uk; Kötter, Peter; Krug, Daniel; Masschelein, Joleen; Melnik, Alexey V.; Mantovani, Simone M.; Monroe, Emily A.; Moore, Marcus; Moss, Nathan; Nützmann, Hans Wilhelm; Pan, Guohui; Pati, Amrita; Petras, Daniel; Reen, F. Jerry; Rosconi, Federico; Rui, Zhe; Tian, Zhenhua; Tobias, Nicholas J.; Tsunematsu, Yuta; Wiemann, Philipp; Wyckoff, Elizabeth; Yan, Xiaohui; Yim, Grace; Yu, Fengan; Xie, Yunchang; Aigle, Bertrand; Apel, Alexander K.; Balibar, Carl J.; Balskus, Emily P.; Barona-Gómez, Francisco; Bechthold, Andreas; Bode, Helge B.; Borriss, Rainer; Brady, Sean F.; Brakhage, Axel A.; Caffrey, Patrick; Cheng, Yi Qiang; Clardy, Jon; Cox, Russell J.; De Mot, René; Donadio, Stefano; Donia, Mohamed S.; Van Der Donk, Wilfred A.; Dorrestein, Pieter C.; Doyle, Sean; Driessen, Arnold J.M.; Ehling-Schulz, Monika; Entian, Karl Dieter; Fischbach, Michael A.; Gerwick, Lena; Gerwick, William H.; Gross, Harald; Gust, Bertolt; Hertweck, Christian; Höfte, Monica; Jensen, Susan E.; Ju, Jianhua; Katz, Leonard; Kaysser, Leonard; Klassen, Jonathan L.; Keller, Nancy P.; Kormanec, Jan; Kuipers, Oscar P.; Kuzuyama, Tomohisa; Kyrpides, Nikos C.; Kwon, Hyung Jin; Lautru, Sylvie; Lavigne, Rob; Lee, Chia Y.; Linquan, Bai; Liu, Xinyu; Liu, Wen; Luzhetskyy, Andriy; Mahmud, Taifo; Mast, Yvonne; Méndez, Carmen; Metsä-Ketelä, Mikko; Micklefield, Jason; Mitchell, Douglas A.; Moore, Bradley S.; Moreira, Leonilde M.; Müller, Rolf; Neilan, Brett A.; Nett, Markus; Nielsen, Jens; O'Gara, Fergal; Oikawa, Hideaki; Osbourn, Anne; Osburne, Marcia S.; Ostash, Bohdan; Payne, Shelley M.; Pernodet, Jean Luc; Petricek, Miroslav; Piel, Jörn; Ploux, Olivier; Raaijmakers, Jos M.; Salas, José A.; Schmitt, Esther K.; Scott, Barry; Seipke, Ryan F.; Shen, Ben; Sherman, David H.; Sivonen, Kaarina; Smanski, Michael J.; Sosio, Margherita; Stegmann, Evi; Süssmuth, Roderich D.; Tahlan, Kapil; Thomas, Christopher M.; Tang, Yi; Truman, Andrew W.; Viaud, Muriel; Walton, Jonathan D.; Walsh, Christopher T.; Weber, Tilmann; Van Wezel, Gilles P.; Wilkinson, Barrie; Willey, Joanne M.; Wohlleben, Wolfgang; Wright, Gerard D.; Ziemert, Nadine; Zhang, Changsheng; Zotchev, Sergey B.; Breitling, Rainer; Takano, Eriko; Glöckner, Frank Oliver.

In: Nature chemical biology, Vol. 11, No. 9, 18.08.2015, p. 625-631.

Research output: Contribution to journalReview article

Medema, MH, Kottmann, R, Yilmaz, P, Cummings, M, Biggins, JB, Blin, K, De Bruijn, I, Chooi, YH, Claesen, J, Coates, RC, Cruz-Morales, P, Duddela, S, Düsterhus, S, Edwards, DJ, Fewer, DP, Garg, N, Geiger, C, Gomez-Escribano, JP, Greule, A, Hadjithomas, M, Haines, AS, Helfrich, EJN, Hillwig, ML, Ishida, K, Jones, AC, Jones, CS, Jungmann, K, Kegler, C, Kim, HU, Kötter, P, Krug, D, Masschelein, J, Melnik, AV, Mantovani, SM, Monroe, EA, Moore, M, Moss, N, Nützmann, HW, Pan, G, Pati, A, Petras, D, Reen, FJ, Rosconi, F, Rui, Z, Tian, Z, Tobias, NJ, Tsunematsu, Y, Wiemann, P, Wyckoff, E, Yan, X, Yim, G, Yu, F, Xie, Y, Aigle, B, Apel, AK, Balibar, CJ, Balskus, EP, Barona-Gómez, F, Bechthold, A, Bode, HB, Borriss, R, Brady, SF, Brakhage, AA, Caffrey, P, Cheng, YQ, Clardy, J, Cox, RJ, De Mot, R, Donadio, S, Donia, MS, Van Der Donk, WA, Dorrestein, PC, Doyle, S, Driessen, AJM, Ehling-Schulz, M, Entian, KD, Fischbach, MA, Gerwick, L, Gerwick, WH, Gross, H, Gust, B, Hertweck, C, Höfte, M, Jensen, SE, Ju, J, Katz, L, Kaysser, L, Klassen, JL, Keller, NP, Kormanec, J, Kuipers, OP, Kuzuyama, T, Kyrpides, NC, Kwon, HJ, Lautru, S, Lavigne, R, Lee, CY, Linquan, B, Liu, X, Liu, W, Luzhetskyy, A, Mahmud, T, Mast, Y, Méndez, C, Metsä-Ketelä, M, Micklefield, J, Mitchell, DA, Moore, BS, Moreira, LM, Müller, R, Neilan, BA, Nett, M, Nielsen, J, O'Gara, F, Oikawa, H, Osbourn, A, Osburne, MS, Ostash, B, Payne, SM, Pernodet, JL, Petricek, M, Piel, J, Ploux, O, Raaijmakers, JM, Salas, JA, Schmitt, EK, Scott, B, Seipke, RF, Shen, B, Sherman, DH, Sivonen, K, Smanski, MJ, Sosio, M, Stegmann, E, Süssmuth, RD, Tahlan, K, Thomas, CM, Tang, Y, Truman, AW, Viaud, M, Walton, JD, Walsh, CT, Weber, T, Van Wezel, GP, Wilkinson, B, Willey, JM, Wohlleben, W, Wright, GD, Ziemert, N, Zhang, C, Zotchev, SB, Breitling, R, Takano, E & Glöckner, FO 2015, 'Minimum Information about a Biosynthetic Gene cluster', Nature chemical biology, vol. 11, no. 9, pp. 625-631. https://doi.org/10.1038/nchembio.1890
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K et al. Minimum Information about a Biosynthetic Gene cluster. Nature chemical biology. 2015 Aug 18;11(9):625-631. https://doi.org/10.1038/nchembio.1890
Medema, Marnix H. ; Kottmann, Renzo ; Yilmaz, Pelin ; Cummings, Matthew ; Biggins, John B. ; Blin, Kai ; De Bruijn, Irene ; Chooi, Yit Heng ; Claesen, Jan ; Coates, R. Cameron ; Cruz-Morales, Pablo ; Duddela, Srikanth ; Düsterhus, Stephanie ; Edwards, Daniel J. ; Fewer, David P. ; Garg, Neha ; Geiger, Christoph ; Gomez-Escribano, Juan Pablo ; Greule, Anja ; Hadjithomas, Michalis ; Haines, Anthony S. ; Helfrich, Eric J.N. ; Hillwig, Matthew L. ; Ishida, Keishi ; Jones, Adam C. ; Jones, Carla S. ; Jungmann, Katrin ; Kegler, Carsten ; Kim, Hyun Uk ; Kötter, Peter ; Krug, Daniel ; Masschelein, Joleen ; Melnik, Alexey V. ; Mantovani, Simone M. ; Monroe, Emily A. ; Moore, Marcus ; Moss, Nathan ; Nützmann, Hans Wilhelm ; Pan, Guohui ; Pati, Amrita ; Petras, Daniel ; Reen, F. Jerry ; Rosconi, Federico ; Rui, Zhe ; Tian, Zhenhua ; Tobias, Nicholas J. ; Tsunematsu, Yuta ; Wiemann, Philipp ; Wyckoff, Elizabeth ; Yan, Xiaohui ; Yim, Grace ; Yu, Fengan ; Xie, Yunchang ; Aigle, Bertrand ; Apel, Alexander K. ; Balibar, Carl J. ; Balskus, Emily P. ; Barona-Gómez, Francisco ; Bechthold, Andreas ; Bode, Helge B. ; Borriss, Rainer ; Brady, Sean F. ; Brakhage, Axel A. ; Caffrey, Patrick ; Cheng, Yi Qiang ; Clardy, Jon ; Cox, Russell J. ; De Mot, René ; Donadio, Stefano ; Donia, Mohamed S. ; Van Der Donk, Wilfred A. ; Dorrestein, Pieter C. ; Doyle, Sean ; Driessen, Arnold J.M. ; Ehling-Schulz, Monika ; Entian, Karl Dieter ; Fischbach, Michael A. ; Gerwick, Lena ; Gerwick, William H. ; Gross, Harald ; Gust, Bertolt ; Hertweck, Christian ; Höfte, Monica ; Jensen, Susan E. ; Ju, Jianhua ; Katz, Leonard ; Kaysser, Leonard ; Klassen, Jonathan L. ; Keller, Nancy P. ; Kormanec, Jan ; Kuipers, Oscar P. ; Kuzuyama, Tomohisa ; Kyrpides, Nikos C. ; Kwon, Hyung Jin ; Lautru, Sylvie ; Lavigne, Rob ; Lee, Chia Y. ; Linquan, Bai ; Liu, Xinyu ; Liu, Wen ; Luzhetskyy, Andriy ; Mahmud, Taifo ; Mast, Yvonne ; Méndez, Carmen ; Metsä-Ketelä, Mikko ; Micklefield, Jason ; Mitchell, Douglas A. ; Moore, Bradley S. ; Moreira, Leonilde M. ; Müller, Rolf ; Neilan, Brett A. ; Nett, Markus ; Nielsen, Jens ; O'Gara, Fergal ; Oikawa, Hideaki ; Osbourn, Anne ; Osburne, Marcia S. ; Ostash, Bohdan ; Payne, Shelley M. ; Pernodet, Jean Luc ; Petricek, Miroslav ; Piel, Jörn ; Ploux, Olivier ; Raaijmakers, Jos M. ; Salas, José A. ; Schmitt, Esther K. ; Scott, Barry ; Seipke, Ryan F. ; Shen, Ben ; Sherman, David H. ; Sivonen, Kaarina ; Smanski, Michael J. ; Sosio, Margherita ; Stegmann, Evi ; Süssmuth, Roderich D. ; Tahlan, Kapil ; Thomas, Christopher M. ; Tang, Yi ; Truman, Andrew W. ; Viaud, Muriel ; Walton, Jonathan D. ; Walsh, Christopher T. ; Weber, Tilmann ; Van Wezel, Gilles P. ; Wilkinson, Barrie ; Willey, Joanne M. ; Wohlleben, Wolfgang ; Wright, Gerard D. ; Ziemert, Nadine ; Zhang, Changsheng ; Zotchev, Sergey B. ; Breitling, Rainer ; Takano, Eriko ; Glöckner, Frank Oliver. / Minimum Information about a Biosynthetic Gene cluster. In: Nature chemical biology. 2015 ; Vol. 11, No. 9. pp. 625-631.
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title = "Minimum Information about a Biosynthetic Gene cluster",
abstract = "A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.",
author = "Medema, {Marnix H.} and Renzo Kottmann and Pelin Yilmaz and Matthew Cummings and Biggins, {John B.} and Kai Blin and {De Bruijn}, Irene and Chooi, {Yit Heng} and Jan Claesen and Coates, {R. Cameron} and Pablo Cruz-Morales and Srikanth Duddela and Stephanie D{\"u}sterhus and Edwards, {Daniel J.} and Fewer, {David P.} and Neha Garg and Christoph Geiger and Gomez-Escribano, {Juan Pablo} and Anja Greule and Michalis Hadjithomas and Haines, {Anthony S.} and Helfrich, {Eric J.N.} and Hillwig, {Matthew L.} and Keishi Ishida and Jones, {Adam C.} and Jones, {Carla S.} and Katrin Jungmann and Carsten Kegler and Kim, {Hyun Uk} and Peter K{\"o}tter and Daniel Krug and Joleen Masschelein and Melnik, {Alexey V.} and Mantovani, {Simone M.} and Monroe, {Emily A.} and Marcus Moore and Nathan Moss and N{\"u}tzmann, {Hans Wilhelm} and Guohui Pan and Amrita Pati and Daniel Petras and Reen, {F. Jerry} and Federico Rosconi and Zhe Rui and Zhenhua Tian and Tobias, {Nicholas J.} and Yuta Tsunematsu and Philipp Wiemann and Elizabeth Wyckoff and Xiaohui Yan and Grace Yim and Fengan Yu and Yunchang Xie and Bertrand Aigle and Apel, {Alexander K.} and Balibar, {Carl J.} and Balskus, {Emily P.} and Francisco Barona-G{\'o}mez and Andreas Bechthold and Bode, {Helge B.} and Rainer Borriss and Brady, {Sean F.} and Brakhage, {Axel A.} and Patrick Caffrey and Cheng, {Yi Qiang} and Jon Clardy and Cox, {Russell J.} and {De Mot}, Ren{\'e} and Stefano Donadio and Donia, {Mohamed S.} and {Van Der Donk}, {Wilfred A.} and Dorrestein, {Pieter C.} and Sean Doyle and Driessen, {Arnold J.M.} and Monika Ehling-Schulz and Entian, {Karl Dieter} and Fischbach, {Michael A.} and Lena Gerwick and Gerwick, {William H.} and Harald Gross and Bertolt Gust and Christian Hertweck and Monica H{\"o}fte and Jensen, {Susan E.} and Jianhua Ju and Leonard Katz and Leonard Kaysser and Klassen, {Jonathan L.} and Keller, {Nancy P.} and Jan Kormanec and Kuipers, {Oscar P.} and Tomohisa Kuzuyama and Kyrpides, {Nikos C.} and Kwon, {Hyung Jin} and Sylvie Lautru and Rob Lavigne and Lee, {Chia Y.} and Bai Linquan and Xinyu Liu and Wen Liu and Andriy Luzhetskyy and Taifo Mahmud and Yvonne Mast and Carmen M{\'e}ndez and Mikko Mets{\"a}-Ketel{\"a} and Jason Micklefield and Mitchell, {Douglas A.} and Moore, {Bradley S.} and Moreira, {Leonilde M.} and Rolf M{\"u}ller and Neilan, {Brett A.} and Markus Nett and Jens Nielsen and Fergal O'Gara and Hideaki Oikawa and Anne Osbourn and Osburne, {Marcia S.} and Bohdan Ostash and Payne, {Shelley M.} and Pernodet, {Jean Luc} and Miroslav Petricek and J{\"o}rn Piel and Olivier Ploux and Raaijmakers, {Jos M.} and Salas, {Jos{\'e} A.} and Schmitt, {Esther K.} and Barry Scott and Seipke, {Ryan F.} and Ben Shen and Sherman, {David H.} and Kaarina Sivonen and Smanski, {Michael J.} and Margherita Sosio and Evi Stegmann and S{\"u}ssmuth, {Roderich D.} and Kapil Tahlan and Thomas, {Christopher M.} and Yi Tang and Truman, {Andrew W.} and Muriel Viaud and Walton, {Jonathan D.} and Walsh, {Christopher T.} and Tilmann Weber and {Van Wezel}, {Gilles P.} and Barrie Wilkinson and Willey, {Joanne M.} and Wolfgang Wohlleben and Wright, {Gerard D.} and Nadine Ziemert and Changsheng Zhang and Zotchev, {Sergey B.} and Rainer Breitling and Eriko Takano and Gl{\"o}ckner, {Frank Oliver}",
year = "2015",
month = "8",
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T1 - Minimum Information about a Biosynthetic Gene cluster

AU - Medema, Marnix H.

AU - Kottmann, Renzo

AU - Yilmaz, Pelin

AU - Cummings, Matthew

AU - Biggins, John B.

AU - Blin, Kai

AU - De Bruijn, Irene

AU - Chooi, Yit Heng

AU - Claesen, Jan

AU - Coates, R. Cameron

AU - Cruz-Morales, Pablo

AU - Duddela, Srikanth

AU - Düsterhus, Stephanie

AU - Edwards, Daniel J.

AU - Fewer, David P.

AU - Garg, Neha

AU - Geiger, Christoph

AU - Gomez-Escribano, Juan Pablo

AU - Greule, Anja

AU - Hadjithomas, Michalis

AU - Haines, Anthony S.

AU - Helfrich, Eric J.N.

AU - Hillwig, Matthew L.

AU - Ishida, Keishi

AU - Jones, Adam C.

AU - Jones, Carla S.

AU - Jungmann, Katrin

AU - Kegler, Carsten

AU - Kim, Hyun Uk

AU - Kötter, Peter

AU - Krug, Daniel

AU - Masschelein, Joleen

AU - Melnik, Alexey V.

AU - Mantovani, Simone M.

AU - Monroe, Emily A.

AU - Moore, Marcus

AU - Moss, Nathan

AU - Nützmann, Hans Wilhelm

AU - Pan, Guohui

AU - Pati, Amrita

AU - Petras, Daniel

AU - Reen, F. Jerry

AU - Rosconi, Federico

AU - Rui, Zhe

AU - Tian, Zhenhua

AU - Tobias, Nicholas J.

AU - Tsunematsu, Yuta

AU - Wiemann, Philipp

AU - Wyckoff, Elizabeth

AU - Yan, Xiaohui

AU - Yim, Grace

AU - Yu, Fengan

AU - Xie, Yunchang

AU - Aigle, Bertrand

AU - Apel, Alexander K.

AU - Balibar, Carl J.

AU - Balskus, Emily P.

AU - Barona-Gómez, Francisco

AU - Bechthold, Andreas

AU - Bode, Helge B.

AU - Borriss, Rainer

AU - Brady, Sean F.

AU - Brakhage, Axel A.

AU - Caffrey, Patrick

AU - Cheng, Yi Qiang

AU - Clardy, Jon

AU - Cox, Russell J.

AU - De Mot, René

AU - Donadio, Stefano

AU - Donia, Mohamed S.

AU - Van Der Donk, Wilfred A.

AU - Dorrestein, Pieter C.

AU - Doyle, Sean

AU - Driessen, Arnold J.M.

AU - Ehling-Schulz, Monika

AU - Entian, Karl Dieter

AU - Fischbach, Michael A.

AU - Gerwick, Lena

AU - Gerwick, William H.

AU - Gross, Harald

AU - Gust, Bertolt

AU - Hertweck, Christian

AU - Höfte, Monica

AU - Jensen, Susan E.

AU - Ju, Jianhua

AU - Katz, Leonard

AU - Kaysser, Leonard

AU - Klassen, Jonathan L.

AU - Keller, Nancy P.

AU - Kormanec, Jan

AU - Kuipers, Oscar P.

AU - Kuzuyama, Tomohisa

AU - Kyrpides, Nikos C.

AU - Kwon, Hyung Jin

AU - Lautru, Sylvie

AU - Lavigne, Rob

AU - Lee, Chia Y.

AU - Linquan, Bai

AU - Liu, Xinyu

AU - Liu, Wen

AU - Luzhetskyy, Andriy

AU - Mahmud, Taifo

AU - Mast, Yvonne

AU - Méndez, Carmen

AU - Metsä-Ketelä, Mikko

AU - Micklefield, Jason

AU - Mitchell, Douglas A.

AU - Moore, Bradley S.

AU - Moreira, Leonilde M.

AU - Müller, Rolf

AU - Neilan, Brett A.

AU - Nett, Markus

AU - Nielsen, Jens

AU - O'Gara, Fergal

AU - Oikawa, Hideaki

AU - Osbourn, Anne

AU - Osburne, Marcia S.

AU - Ostash, Bohdan

AU - Payne, Shelley M.

AU - Pernodet, Jean Luc

AU - Petricek, Miroslav

AU - Piel, Jörn

AU - Ploux, Olivier

AU - Raaijmakers, Jos M.

AU - Salas, José A.

AU - Schmitt, Esther K.

AU - Scott, Barry

AU - Seipke, Ryan F.

AU - Shen, Ben

AU - Sherman, David H.

AU - Sivonen, Kaarina

AU - Smanski, Michael J.

AU - Sosio, Margherita

AU - Stegmann, Evi

AU - Süssmuth, Roderich D.

AU - Tahlan, Kapil

AU - Thomas, Christopher M.

AU - Tang, Yi

AU - Truman, Andrew W.

AU - Viaud, Muriel

AU - Walton, Jonathan D.

AU - Walsh, Christopher T.

AU - Weber, Tilmann

AU - Van Wezel, Gilles P.

AU - Wilkinson, Barrie

AU - Willey, Joanne M.

AU - Wohlleben, Wolfgang

AU - Wright, Gerard D.

AU - Ziemert, Nadine

AU - Zhang, Changsheng

AU - Zotchev, Sergey B.

AU - Breitling, Rainer

AU - Takano, Eriko

AU - Glöckner, Frank Oliver

PY - 2015/8/18

Y1 - 2015/8/18

N2 - A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

AB - A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

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JF - Nature Chemical Biology

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