Mineralized collagen scaffolds for regenerative engineering applications

Vasiliki Kolliopoulos, Brendan AC Harley

Research output: Contribution to journalReview articlepeer-review


Collagen is a primary constituent of the tissue extracellular matrix. As a result, collagen has been a common component of tissue engineering biomaterials, including those to promote bone regeneration or to investigate cell-material interactions in the context of bone homeostasis or disease. This review summarizes key considerations regarding current state-of-the-art design and use of collagen biomaterials for these applications. We also describe strategic opportunities for collagen biomaterials to address a new era of challenges, including immunomodulation and appropriate consideration of sex and other patient characteristics in biomaterial design.

Original languageEnglish (US)
Article number103080
JournalCurrent Opinion in Biotechnology
StatePublished - Apr 2024

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biomedical Engineering


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