Mineral binding peptides with enhanced binding stability in serum

Jae Sung Lee, Xiaohua Yu, Amy J. Wagoner Johnson, William L. Murphy

Research output: Contribution to journalArticlepeer-review


Although calcium phosphate (CaP) binding peptides are used to link orthobiologics to orthopedic biomaterials, their binding stability in physiological environment is still unknown. In this study, we investigate the binding capability of a series of CaP-binding peptides and their binding stability in serum solutions, which are selected to resemble physiological conditions. The findings in this study may be applicable for designing robust orthobiologic delivery systems.

Original languageEnglish (US)
Pages (from-to)663-668
Number of pages6
JournalBiomaterials Science
Issue number4
StatePublished - Apr 2017

ASJC Scopus subject areas

  • Biomedical Engineering
  • Materials Science(all)


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