Microwave-Mediated Synthesis of Anticarcinogenic Isoflavones from Soybeans

Yu Chen Chang; Muraleedharan G. Nair; Ross C. Santell; William G. Helferich

doi:10.1021/jf00045a007

Microwave-Mediated Synthesis of Anticarcinogenic Isoflavones from Soybeans

Yu Chen Chang, Muraleedharan G. Nair, Ross C. Santell, William G. Helferich

Research output: Contribution to journal › Article › peer-review

Abstract

Soybean isoflavonoids, 7,4′-dihydroxyisoflavone (daidzein), 7-hydroxy-4′-methoxyisoflavone (formononetin), 5,7,4′-trihydroxyisoflavone (genistein), and 5,7-dihydroxy-4′-methoxyisoflavone (biochanin A), were synthesized in high yields by cyclization of their corresponding ketones in a conventional microwave oven.

Original language	English (US)
Pages (from-to)	1869-1871
Number of pages	3
Journal	Journal of Agricultural and Food Chemistry
Volume	42
Issue number	9
DOIs	https://doi.org/10.1021/jf00045a007
State	Published - Sep 1 1994
Externally published	Yes

Keywords

Microwave synthesis
biochanin A
daidzein
formononetin
genistein
isoflavones

ASJC Scopus subject areas

Chemistry(all)
Agricultural and Biological Sciences(all)

Online availability

10.1021/jf00045a007

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title = "Microwave-Mediated Synthesis of Anticarcinogenic Isoflavones from Soybeans",

abstract = "Soybean isoflavonoids, 7,4′-dihydroxyisoflavone (daidzein), 7-hydroxy-4′-methoxyisoflavone (formononetin), 5,7,4′-trihydroxyisoflavone (genistein), and 5,7-dihydroxy-4′-methoxyisoflavone (biochanin A), were synthesized in high yields by cyclization of their corresponding ketones in a conventional microwave oven.",

keywords = "Microwave synthesis, biochanin A, daidzein, formononetin, genistein, isoflavones",

author = "Chang, {Yu Chen} and Nair, {Muraleedharan G.} and Santell, {Ross C.} and Helferich, {William G.}",

year = "1994",

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journal = "Journal of Agricultural and Food Chemistry",

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T1 - Microwave-Mediated Synthesis of Anticarcinogenic Isoflavones from Soybeans

AU - Chang, Yu Chen

AU - Nair, Muraleedharan G.

AU - Santell, Ross C.

AU - Helferich, William G.

PY - 1994/9/1

Y1 - 1994/9/1

N2 - Soybean isoflavonoids, 7,4′-dihydroxyisoflavone (daidzein), 7-hydroxy-4′-methoxyisoflavone (formononetin), 5,7,4′-trihydroxyisoflavone (genistein), and 5,7-dihydroxy-4′-methoxyisoflavone (biochanin A), were synthesized in high yields by cyclization of their corresponding ketones in a conventional microwave oven.

AB - Soybean isoflavonoids, 7,4′-dihydroxyisoflavone (daidzein), 7-hydroxy-4′-methoxyisoflavone (formononetin), 5,7,4′-trihydroxyisoflavone (genistein), and 5,7-dihydroxy-4′-methoxyisoflavone (biochanin A), were synthesized in high yields by cyclization of their corresponding ketones in a conventional microwave oven.

KW - Microwave synthesis

KW - biochanin A

KW - daidzein

KW - formononetin

KW - genistein

KW - isoflavones

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DO - 10.1021/jf00045a007

M3 - Article

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SN - 0021-8561

VL - 42

SP - 1869

EP - 1871

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

IS - 9

ER -

Microwave-Mediated Synthesis of Anticarcinogenic Isoflavones from Soybeans

Abstract

Keywords

ASJC Scopus subject areas

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