TY - JOUR
T1 - Microplate-based label-free screening on the BIND system
AU - Cunningham, Brian T.
AU - Laing, Lance
PY - 2007/9
Y1 - 2007/9
N2 - A new type of label-free optical biosensor is described that is incorporated into standard format (96, 384, and 1536-well) microplates to enable highly sensitive, high throughput screening of biochemical interactions involving small molecules, proteins, and cells. The use of the biosensor microplates and associated detection instrumentation is highlighted for the screening of a small molecule library. Several additional applications that are under development are described, as well as the key issues that will drive the future adoption of the technology.
AB - A new type of label-free optical biosensor is described that is incorporated into standard format (96, 384, and 1536-well) microplates to enable highly sensitive, high throughput screening of biochemical interactions involving small molecules, proteins, and cells. The use of the biosensor microplates and associated detection instrumentation is highlighted for the screening of a small molecule library. Several additional applications that are under development are described, as well as the key issues that will drive the future adoption of the technology.
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M3 - Review article
AN - SCOPUS:35348865491
SN - 2032-2887
VL - 19
SP - 14
EP - 18
JO - Bio Tech International
JF - Bio Tech International
IS - 4
ER -