Microinstruments for single cellular studies

Shengyuan Yang, Taher Saif

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A class of MEMS devices for manipulating single living cells and measuring the cell mechanical response is described. They consist of a probe and flexible beams. The probe is used to contact and manipulate the cell and the beams to monitor cell force response. The devices are used to disturb green fluorescent protein-actin transfected fibroblasts to study depolymerization and remodeling of the actin network in the cells in situ.

Original languageEnglish (US)
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
Subtitle of host publication9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages900-902
Number of pages3
ISBN (Print)0974361119, 9780974361116
StatePublished - Jan 1 2005
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
Duration: Oct 9 2005Oct 13 2005

Publication series

NameMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume1

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
CountryUnited States
CityBoston, MA
Period10/9/0510/13/05

Keywords

  • Actin network
  • BioMEMS
  • Mechanical behavior
  • Single living cells

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Yang, S., & Saif, T. (2005). Microinstruments for single cellular studies. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 900-902). (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences; Vol. 1). Transducer Research Foundation.