Microfluidic device as a new platform for immunofluorescent detection of viruses

Wen Tso Liu, Liang Zhu, Qi Wei Qin, Qing Zhang, Hanhua Feng, Simon Ang

Research output: Contribution to journalArticlepeer-review


A bead-based microfluidic device was developed and demonstrated to achieve rapid and sensitive enzyme-linked immunosorbent assay (ELISA) with quantum dots as the labeling fluorophore for virus detection. In comparison to standard ELISA performed on the same virus, the minimal detectable concentration of the target virus was improved from 360 to 22 ng mL-1, the detection time was shortened from > 3.25 h to < 30 min, and the amount of antibody consumed was reduced by a factor of 14.3.

Original languageEnglish (US)
Pages (from-to)1327-1330
Number of pages4
JournalLab on a chip
Issue number11
StatePublished - Nov 2005
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering


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