Microfluidic assembly of homogeneous and janus colloid-filled hydrogel granules

Robert F. Shepherd, Jacinta C. Conrad, Summer K. Rhodes, Darren R. Link, Manuel Marquez, David A. Weitz, Jennifer A. Lewis

Research output: Contribution to journalArticlepeer-review


The microfluidic assembly of colloid-filled hydrogel granules of varying shape and composition is described. First, drops are formed by shearing a concentrated colloidal microsphere-acrylamide suspension in a continuous oil phase using a sheath-flow device. Both homogeneous and Janus (hemispherically distinct) spheres and disks are produced by confining the assembled drops in microchannels of varying geometry. Next, photopolymerization is carried out shortly after drop breakup to preserve their morphology. Representative wet and dried granules are characterized using fluorescence and scanning electron microscopy, respectively. Our approach offers a facile route for assembling colloid-filled hydrogel granules with controlled shape and composition.

Original languageEnglish (US)
Pages (from-to)8618-8622
Number of pages5
Issue number21
StatePublished - Oct 10 2006

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry


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