TY - JOUR
T1 - Microelectrode Recording of Tissue Neural Oscillations for a Bionic Olfactory Biosensor
AU - Liu, Qingjun
AU - Zhang, Fenni
AU - Hu, Ning
AU - Wang, Hua
AU - Hsia, Kuen Jimmy
AU - Wang, Ping
N1 - Funding Information:
This work was supported by the National Natural Science Foundation of China (Grant No. 81071226, 60725102), the Research on Public Welfare Technology Application Projects of Zhejiang Province, China (No. 2011C23096), the Zhejiang Provincial Natural Science Foundation of China (No. Y2100684), and the Fundamental Research Funds for the Central Universities.
PY - 2012/12
Y1 - 2012/12
N2 - In olfactory research, neural oscillations exhibit excellent temporal regularity, which are functional and necessary at the physiological and cognitive levels. In this paper, we employed a bionic tissue biosensor which treats intact epithelium as sensing element to record the olfactory oscillations extracellularly. After being stimulated by odorant of butanedione, the olfactory receptor neurons generated different kinds of oscillations, which can be described as pulse firing oscillation, transient firing oscillation, superposed firing oscillation, and sustained firing oscillation, according to their temporal appearances respectively. With a time-frequency analysis of sonogram, the oscillations also demonstrated different frequency properties, such as δ, θ, α, β and γ oscillations. The results suggest that the bionic biosensor cooperated with sonogram analysis can well improve the investigation of olfactory oscillations, and provide a novel model for artificial olfaction sensor design.
AB - In olfactory research, neural oscillations exhibit excellent temporal regularity, which are functional and necessary at the physiological and cognitive levels. In this paper, we employed a bionic tissue biosensor which treats intact epithelium as sensing element to record the olfactory oscillations extracellularly. After being stimulated by odorant of butanedione, the olfactory receptor neurons generated different kinds of oscillations, which can be described as pulse firing oscillation, transient firing oscillation, superposed firing oscillation, and sustained firing oscillation, according to their temporal appearances respectively. With a time-frequency analysis of sonogram, the oscillations also demonstrated different frequency properties, such as δ, θ, α, β and γ oscillations. The results suggest that the bionic biosensor cooperated with sonogram analysis can well improve the investigation of olfactory oscillations, and provide a novel model for artificial olfaction sensor design.
KW - Bionic sensor
KW - Microelectrode array (MEA)
KW - Neural oscillation
KW - Olfactory biosensor
KW - Olfactory epithelium
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U2 - 10.1016/S1672-6529(11)60146-7
DO - 10.1016/S1672-6529(11)60146-7
M3 - Article
AN - SCOPUS:84867851113
SN - 1672-6529
VL - 9
SP - 494
EP - 500
JO - Journal of Bionic Engineering
JF - Journal of Bionic Engineering
IS - 4
ER -