Microbial sialidases: does bigger always mean better?

Research output: Contribution to journalReview articlepeer-review


Sialidases are a superfamily of N-acylneuraminate-releasing (sialic-acid-releasing) exoglycosidases found mainly in higher eukaryotes and in some, mostly pathogenic, viruses, bacteria and protozoans. The functions of sialidases are poorly understood and, until recently, their biochemical and evolutionary relationships were unclear. A comparative approach has demonstrated the remarkable similarities and differences between nonviral sialidases, and is providing clues about their functions.

Original languageEnglish (US)
Pages (from-to)271-277
Number of pages7
JournalTrends in Microbiology
Issue number8
StatePublished - Aug 1994

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Virology
  • Microbiology


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