Abstract

Within the first few microseconds following a charged particle traversal of a cell, numerous oxygen and nitrogen radicals are formed along the track. Presented here is a method, using capillary electrophoresis, for simultaneous measurement, within an individual cell, of specific reactive oxygen species, such as the superoxide radical (O2) as well as the native and oxidised forms of glutathione, an ubiquitous anti-oxidant that assists the cell in coping with these species. Preliminary data are presented as well as plans for integrating this system into the charged particle microbeam at Columbia University.

Original languageEnglish (US)
Article numberncv148
Pages (from-to)188-191
Number of pages4
JournalRadiation Protection Dosimetry
Volume166
Issue number1-4
DOIs
StatePublished - Sep 1 2015

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ASJC Scopus subject areas

  • Radiation
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Public Health, Environmental and Occupational Health

Cite this

Garty, G., Ehsan, M. U., Buonanno, M., Yang, Z., Sweedler, J. V., & Brenner, D. J. (2015). Microbeam-coupled capillary electrophoresis. Radiation Protection Dosimetry, 166(1-4), 188-191. [ncv148]. https://doi.org/10.1093/rpd/ncv148