Methods and devices for detection of trimethylamine (TMA) and trimethylamine oxide (TMAO)

Kenneth S. Suslick (Inventor), Zheng Li (Inventor), Maria K LaGasse (Inventor)

Research output: Patent

Abstract

The present disclosure provides methods for detection and quantification of trimethylamine (TMA) or trimethylamine oxide (TMAO) comprising passing a sample over a sensor comprising a substrate having a plurality of chemically responsive dyes selected from the following classes of chemically responsive dyes: metal-containing dyes, pH indicators, or solvatochromic/vapochromic dyes. The disclosure also provides devices and sensors for the detection and quantification of TMA, and methods of diagnosing a subject having trimethylaminuria (TMAU).
Original languageEnglish (US)
U.S. patent number11346829
Filing date5/17/17
StatePublished - May 31 2022

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