Methocarbamol CRI for symptomatic treatment of pyrethroid intoxication: A report of three cases

William E. Draper, Luiz Bolfer, Emily Cottam, Maureen McMichael, Thomas Schubert

Research output: Contribution to journalArticlepeer-review


Pyrethroids are popular for use in companion animals due to their relatively low mammalian toxicity and efficacy against arthropods. Nonetheless, pyrethroid intoxication has been reported in cats and dogs, and cats appear to bemore susceptible due to difficulty in biotransformation and excretion of pyrethroids. Pyrethroid intoxications are generally due to either the improper use or accidental ingestion of approved products. Methocarbamol, given as intermittent injections, is a common first-line treatment choice for the tremors associated with pyrethroid intoxication. Two cats and one dog were treated with amethocarbamol continuous rate infusion (CRI) for pyrethroid intoxication. Clinical signs of toxicity resolvedwithin a few hr in all three cases, with no adverse drug effects. A methocarbamol CRI can be considered in animals presenting with pyrethroid intoxication.

Original languageEnglish (US)
Pages (from-to)325-328
Number of pages4
JournalJournal of the American Animal Hospital Association
Issue number5
StatePublished - 2013


  • CRI continuous rate infusion
  • ICU intensive care unit
  • PO per os

ASJC Scopus subject areas

  • General Medicine


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