The potential advantages of infrared spectroscopic imaging for examination of cells and tissue biopsies for cancer histopathology is high, however there are fundamental limitations of FTIR that must first be addressed. One limitation is that Infrared spectroscopy lacks the sensitivity to detect biomarkers of disease directly. With cancer being one of the leading causes of death and its increasing prevalence, it is important to develop tools that can rapidly screen and enable rapid and simultaneous fingerprinting of biologic content and metabolic state. To address these limitations, probed Infrared spectroscopy is being explored. We report the successful synthesis, characterization, and application of metal carbonyl loaded nanoparticle probes for the detection of breast cancer biomarkers.

Original languageEnglish (US)
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI
EditorsDror Fixler, Sebastian Wachsmann-Hogiu
ISBN (Electronic)9781510669758
StatePublished - 2024
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI 2024 - San Francisco, United States
Duration: Jan 28 2024 → …

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI 2024
Country/TerritoryUnited States
CitySan Francisco
Period1/28/24 → …


  • Biomarkers
  • Breast Cancer
  • Metal Carbonyl
  • Nanoparticle

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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