Meningioma in a bengal tiger (Panthera Tigris Tigris)

Erin Y. Akin, Wes A. Baumgartner, Jung Keun Lee, Michaela J. Beasley

Research output: Contribution to journalArticlepeer-review


A 17-yr-old female ovariectomized Bengal tiger (Panthera tigris tigris) was presented dead on arrival to the Mississippi State University College of Veterinary Medicine. The tiger was a resident of a sanctuary for big cats and had a history of juvenile-onset blindness of unknown cause. The tiger suffered two seizures the morning of presentation and expired shortly after resolution of the second seizure. Gross necropsy findings included a meningioma attached to the left frontal bone and associated with the left frontal lobe. Histologically, the mass was composed of meningothelial cells arising from the meninges, forming whorls and streams. Cells often formed syncytia and psammoma bodies were present. Neoplastic cells were immunohistochemically positive for vimentin, S100, and cytokeratin, but negative for GFAP. All findings were consistent with a meningioma. This is the first documentation of a meningioma in a Bengal tiger.

Original languageEnglish (US)
Pages (from-to)761-764
Number of pages4
JournalJournal of Zoo and Wildlife Medicine
Issue number3
StatePublished - Sep 2013
Externally publishedYes


  • Meningioma
  • Neoplasia
  • Panthera tigris tigris
  • Seizure
  • Tiger

ASJC Scopus subject areas

  • Animal Science and Zoology
  • General Veterinary


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