TY - GEN
T1 - MEMS based sensors to explore the role of tension in axons for neuro-transmission
AU - Yang, S.
AU - Siechen, S.
AU - Sung, J.
AU - Chiba, A.
AU - Saif, M Taher A
PY - 2008
Y1 - 2008
N2 - This paper employs MEMS force sensors to explore the role of mechanical tension in neuro transmission. Here, the nervous system of Drosophila (fruit fly) embryo is examined. The accumulation of vesicles that carry neuro transmitter at the synapse between the axons and muscle tissue is measured using florescent technique. The tensile force on axons are measured in vivo. The rest tension in axons is found to be about 1 nN. Increasing the tension by mechanical probing results in increasing vesicle accumulation. The results suggests that nature employs mechanical tension as a means of tuning neuro transmission efficiency, and hence memory formation.
AB - This paper employs MEMS force sensors to explore the role of mechanical tension in neuro transmission. Here, the nervous system of Drosophila (fruit fly) embryo is examined. The accumulation of vesicles that carry neuro transmitter at the synapse between the axons and muscle tissue is measured using florescent technique. The tensile force on axons are measured in vivo. The rest tension in axons is found to be about 1 nN. Increasing the tension by mechanical probing results in increasing vesicle accumulation. The results suggests that nature employs mechanical tension as a means of tuning neuro transmission efficiency, and hence memory formation.
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U2 - 10.1109/MEMSYS.2008.4443654
DO - 10.1109/MEMSYS.2008.4443654
M3 - Conference contribution
AN - SCOPUS:50149105727
SN - 9781424417933
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 308
EP - 310
BT - MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems
T2 - 21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson
Y2 - 13 January 2008 through 17 January 2008
ER -