MEMS based sensors to explore the role of tension in axons for neuro-transmission

S. Yang; S. Siechen; J. Sung; A. Chiba; M Taher A Saif

doi:10.1109/MEMSYS.2008.4443654

MEMS based sensors to explore the role of tension in axons for neuro-transmission

S. Yang, S. Siechen, J. Sung, A. Chiba, M Taher A Saif

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper employs MEMS force sensors to explore the role of mechanical tension in neuro transmission. Here, the nervous system of Drosophila (fruit fly) embryo is examined. The accumulation of vesicles that carry neuro transmitter at the synapse between the axons and muscle tissue is measured using florescent technique. The tensile force on axons are measured in vivo. The rest tension in axons is found to be about 1 nN. Increasing the tension by mechanical probing results in increasing vesicle accumulation. The results suggests that nature employs mechanical tension as a means of tuning neuro transmission efficiency, and hence memory formation.

Original language	English (US)
Title of host publication	MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems
Pages	308-310
Number of pages	3
DOIs	https://doi.org/10.1109/MEMSYS.2008.4443654
State	Published - Aug 29 2008
Event	21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson - Tucson, AZ, United States Duration: Jan 13 2008 → Jan 17 2008

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Other

Other	21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson
Country/Territory	United States
City	Tucson, AZ
Period	1/13/08 → 1/17/08

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

Online availability

10.1109/MEMSYS.2008.4443654

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Yang, S., Siechen, S., Sung, J., Chiba, A., & Saif, M. T. A. (2008). MEMS based sensors to explore the role of tension in axons for neuro-transmission. In MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems (pp. 308-310). [4443654] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2008.4443654

MEMS based sensors to explore the role of tension in axons for neuro-transmission. / Yang, S.; Siechen, S.; Sung, J. et al.

MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems. 2008. p. 308-310 4443654 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Yang, S, Siechen, S, Sung, J, Chiba, A & Saif, MTA 2008, MEMS based sensors to explore the role of tension in axons for neuro-transmission. in MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems., 4443654, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 308-310, 21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson, Tucson, AZ, United States, 1/13/08. https://doi.org/10.1109/MEMSYS.2008.4443654

Yang S, Siechen S, Sung J, Chiba A, Saif MTA. MEMS based sensors to explore the role of tension in axons for neuro-transmission. In MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems. 2008. p. 308-310. 4443654. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2008.4443654

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abstract = "This paper employs MEMS force sensors to explore the role of mechanical tension in neuro transmission. Here, the nervous system of Drosophila (fruit fly) embryo is examined. The accumulation of vesicles that carry neuro transmitter at the synapse between the axons and muscle tissue is measured using florescent technique. The tensile force on axons are measured in vivo. The rest tension in axons is found to be about 1 nN. Increasing the tension by mechanical probing results in increasing vesicle accumulation. The results suggests that nature employs mechanical tension as a means of tuning neuro transmission efficiency, and hence memory formation.",

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MEMS based sensors to explore the role of tension in axons for neuro-transmission

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