Abstract
This paper presents bioMEMS force sensors, consisting of a probe and flexible beams, to study mechanobiological response of single living cells subjected to mechanical injury. Mechanical injuries are simulated by the application of large indentation on the cells by the sensor probe. The green fluorescent protein (GFP) technique is used to visualize the evolution of the actin network in the cells. The lateral indentation force response measurement capability of the sensors is shown. Two new types of remodeling, large buckling of stress fibers and actin agglomeration, in the actin network in a cell due to mechanical stimuli are reported.
| Original language | English (US) |
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| Title of host publication | 19th IEEE International Conference on Micro Electro Mechanical Systems |
| Pages | 20-23 |
| Number of pages | 4 |
| Volume | 2006 |
| State | Published - 2006 |
| Event | 19th IEEE International Conference on Micro Electro Mechanical Systems - Istanbul, Turkey Duration: Jan 22 2006 → Jan 26 2006 |
Other
| Other | 19th IEEE International Conference on Micro Electro Mechanical Systems |
|---|---|
| Country/Territory | Turkey |
| City | Istanbul |
| Period | 1/22/06 → 1/26/06 |
ASJC Scopus subject areas
- Mechanical Engineering
- Electrical and Electronic Engineering
- Control and Systems Engineering