Membrane thickness design of implantable bio-MEMS sensors for the in-situ monitoring of blood flow

C. A. Steeves, Y. L. Young, Z. Liu, A. Bapat, K. Bhalerao, A. B.O. Soboyejo, W. O. Soboyejo

Research output: Contribution to journalArticlepeer-review

Abstract

This paper presents some ideas for the membrane thickness design of of implantable bio-micro-electro-mechanical systems (bio-MEMS) for the in situ monitoring of blood flow. The objective is to develop a smart wireless sensing unit for non-invasive early stenosis detection in heart bypass grafts. The design includes considerations of nonlinear material models, multiscale blood flows, and appropriate analyical models for data interpretation, as well as preliminary studies of the pressure and flow sensing concepts. The paper also examines the use of surface coatings for the design on biocompatibility and non-adhesion of blood platelets and constituents. The implications of the results are discussed for in vivo deployment of such sensor systems.

Original languageEnglish (US)
Pages (from-to)25-37
Number of pages13
JournalJournal of Materials Science: Materials in Medicine
Volume18
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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