Membrane-actin interactions in morphogenesis: Lessons learned from Drosophila cellularization

Anna Marie Sokac; Natalie Biel; Stefano De Renzis

doi:10.1016/j.semcdb.2022.03.028

Membrane-actin interactions in morphogenesis: Lessons learned from Drosophila cellularization

Anna Marie Sokac, Natalie Biel, Stefano De Renzis

Cell and Developmental Biology

Research output: Contribution to journal › Review article › peer-review

Abstract

During morphogenesis, changes in the shapes of individual cells are harnessed to mold an entire tissue. These changes in cell shapes require the coupled remodeling of the plasma membrane and underlying actin cytoskeleton. In this review, we highlight cellularization of the Drosophila embryo as a model system to uncover principles of how membrane and actin dynamics are co-regulated in space and time to drive morphogenesis.

Original language	English (US)
Pages (from-to)	107-122
Number of pages	16
Journal	Seminars in Cell and Developmental Biology
Volume	133
DOIs	https://doi.org/10.1016/j.semcdb.2022.03.028
State	Published - Jan 15 2023

Keywords

Actin
Cortical compartments
Cytokinesis
Endocytosis
Exocytosis
Membrane reservoir
Membrane trafficking
Myosin-2
Phosphoinositides

ASJC Scopus subject areas

Cell Biology
Developmental Biology

Online availability

10.1016/j.semcdb.2022.03.028

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title = "Membrane-actin interactions in morphogenesis: Lessons learned from Drosophila cellularization",

abstract = "During morphogenesis, changes in the shapes of individual cells are harnessed to mold an entire tissue. These changes in cell shapes require the coupled remodeling of the plasma membrane and underlying actin cytoskeleton. In this review, we highlight cellularization of the Drosophila embryo as a model system to uncover principles of how membrane and actin dynamics are co-regulated in space and time to drive morphogenesis.",

keywords = "Actin, Cortical compartments, Cytokinesis, Endocytosis, Exocytosis, Membrane reservoir, Membrane trafficking, Myosin-2, Phosphoinositides",

author = "Sokac, {Anna Marie} and Natalie Biel and {De Renzis}, Stefano",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors",

year = "2023",

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day = "15",

doi = "10.1016/j.semcdb.2022.03.028",

language = "English (US)",

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T1 - Membrane-actin interactions in morphogenesis

T2 - Lessons learned from Drosophila cellularization

AU - Sokac, Anna Marie

AU - Biel, Natalie

AU - De Renzis, Stefano

PY - 2023/1/15

Y1 - 2023/1/15

N2 - During morphogenesis, changes in the shapes of individual cells are harnessed to mold an entire tissue. These changes in cell shapes require the coupled remodeling of the plasma membrane and underlying actin cytoskeleton. In this review, we highlight cellularization of the Drosophila embryo as a model system to uncover principles of how membrane and actin dynamics are co-regulated in space and time to drive morphogenesis.

AB - During morphogenesis, changes in the shapes of individual cells are harnessed to mold an entire tissue. These changes in cell shapes require the coupled remodeling of the plasma membrane and underlying actin cytoskeleton. In this review, we highlight cellularization of the Drosophila embryo as a model system to uncover principles of how membrane and actin dynamics are co-regulated in space and time to drive morphogenesis.

KW - Actin

KW - Cortical compartments

KW - Cytokinesis

KW - Endocytosis

KW - Exocytosis

KW - Membrane reservoir

KW - Membrane trafficking

KW - Myosin-2

KW - Phosphoinositides

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UR - http://www.scopus.com/inward/citedby.url?scp=85127632733&partnerID=8YFLogxK

U2 - 10.1016/j.semcdb.2022.03.028

DO - 10.1016/j.semcdb.2022.03.028

M3 - Review article

C2 - 35396167

AN - SCOPUS:85127632733

SN - 1084-9521

VL - 133

SP - 107

EP - 122

JO - Seminars in Cell and Developmental Biology

JF - Seminars in Cell and Developmental Biology

ER -

Membrane-actin interactions in morphogenesis: Lessons learned from Drosophila cellularization

Abstract

Keywords

ASJC Scopus subject areas

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