Abstract
Poly(ethylene glycol) hydrogels with disulfide linkages are functionalized through applied force. Compression or tension induces bond rupture at the relatively weak disulfide linkages, which will subsequently react through Michael-type addition with an acceptor molecule within the gel. We demonstrate the utility of this approach by patterning cell adhesion proteins through compression of a lithographically structured stamp, where cells predominately adhere to the compressed regions.
Original language | English (US) |
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Pages (from-to) | 447-451 |
Number of pages | 5 |
Journal | Materials Horizons |
Volume | 3 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2016 |
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Process Chemistry and Technology
- Electrical and Electronic Engineering