Mechanistic studies on the substrate-tolerant lanthipeptide synthetase ProcM

Keyphrases

• Mechanistic Studies 100%
• Leader Peptide 100%
• Lanthipeptide Synthetases 100%
• Alkynes 66%
• Thioester 66%
• Substrate Analog 66%
• Lanthipeptide 66%
• Cysteine 33%
• Proton 33%
• Expressed Protein Ligation 33%
• Side Chain 33%
• Dehydration 33%
• Biological Activity 33%
• N-terminus 33%
• Ligation 33%
• Cyclization 33%
• C-terminus 33%
• Synthetic Peptides 33%
• Deuterium Labeling 33%
• Modified Peptide 33%
• Peptide Substrate 33%
• Semi-synthetic 33%
• Substrate Tolerance 33%
• Lanthionine 33%
• Ring Formation 33%
• Cysteine Derivatives 33%
• Copper-catalyzed Azide-alkyne Cycloaddition (CuAAC) 33%
• Proca 33%
• Peptide Natural Products 33%
• Enzymatic Cyclization 33%
• Substrate Peptide 33%

Biochemistry, Genetics and Molecular Biology

• Signal Peptide 100%
• Cysteine 66%
• C-Terminus 66%
• Thioester 66%
• Cyclization 66%
• Substrate Analog 66%
• N-Terminus 33%
• Enzyme 33%
• Cross-Link 33%
• Biological Activity 33%
• Lanthionine 33%

Chemistry

• Alkyne 100%
• Mechanistic Study 100%
• Thioester 66%
• Primary Structure 33%
• Cysteine 33%
• Bioactivity 33%
• Azide 33%
• Deuterium(.) 33%
• Occurrence in Nature 33%
• Cysteine Derivative 33%
• Ring Formation 33%
• Lanthionine 33%