Mechanisms of enteral nutrient-enhanced intestinal adaptation

Kelly A. Tappenden

Research output: Contribution to journalArticle

Abstract

The role of enteral nutrients in maintaining small intestinal structure and function is well established. Evidence that enteral nutrients induce intestinal adaptation include the structural and functional gradient along the length of the healthy intestine, the atrophy and functional compromise induced by fasting and parenteral nutrition, and the enhanced adaptive capacity of the distal intestine following partial enterectomy. Key mechanisms contributing to enteral nutrient-induced intestinal adaptation include nonspecific luminal stimulation and that provided by specific nutrients, "functional workload" induced by polymeric nutrients, potential stimulation of pancreaticobiliary secretions, secretion of humoral mediators, and induction of intestinal hyperemia.

Original languageEnglish (US)
JournalGastroenterology
Volume130
Issue number2 SUPPL.
DOIs
StatePublished - Feb 2006

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Small Intestine
Food
Intestines
Parenteral Nutrition
Hyperemia
Workload
Atrophy
Fasting

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Mechanisms of enteral nutrient-enhanced intestinal adaptation. / Tappenden, Kelly A.

In: Gastroenterology, Vol. 130, No. 2 SUPPL., 02.2006.

Research output: Contribution to journalArticle

Tappenden, Kelly A. / Mechanisms of enteral nutrient-enhanced intestinal adaptation. In: Gastroenterology. 2006 ; Vol. 130, No. 2 SUPPL.
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