Abstract

Direct measurements of the distance-dependent forces between membrane-bound cadherins were used to test current models of homophilic cadherin interactions. The results reveal a complex binding mechanism in which the proteins adhere in multiple alignments that involve more than the amino-terminal domains.

Original languageEnglish (US)
Pages (from-to)587-592
Number of pages6
JournalCurrent Opinion in Cell Biology
Volume12
Issue number5
DOIs
StatePublished - Jan 1 2000

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Cadherins
Membranes
Proteins

ASJC Scopus subject areas

  • Cell Biology

Cite this

Mechanism of homophilic cadherin adhesion. / Leckband, Deborah E; Sivasankar, Sanjeevi.

In: Current Opinion in Cell Biology, Vol. 12, No. 5, 01.01.2000, p. 587-592.

Research output: Contribution to journalReview article

Leckband, Deborah E ; Sivasankar, Sanjeevi. / Mechanism of homophilic cadherin adhesion. In: Current Opinion in Cell Biology. 2000 ; Vol. 12, No. 5. pp. 587-592.
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