Mechanics of vimentin intermediate filaments

Ning Wang, Dimitrijie Stamenovic

Research output: Contribution to journalReview article

Abstract

It is increasingly evident that the cytoskeleton of living cells plays important roles in mechanical and biological functions of the cells. Here we focus on the contribution of intermediate filaments (IFs) to the mechanical behaviors of living cells. Vimentin, a major structural component of IFs in many cell types, is shown to play an important role in vital mechanical and biological functions such as cell contractility, migration, stiffness, stiffening, and proliferation.

Original languageEnglish (US)
Pages (from-to)535-540
Number of pages6
JournalJournal of Muscle Research and Cell Motility
Volume23
Issue number5-6
DOIs
StatePublished - Dec 1 2002
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Cell Biology

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