Measurement of tidal volume using Respiratory Ultrasonic Plethysmography in anaesthetized, mechanically ventilated horses

Elena Russold, Tamas D. Ambrisko, Johannes P. Schramel, Ulrike Auer, Rene Van Den Hoven, Yves P. Moens

Research output: Contribution to journalArticle

Abstract

Objective To compare tidal volume estimations obtained from Respiratory Ultrasonic Plethysmography (RUP) with simultaneous spirometric measurements in anaesthetized, mechanically ventilated horses. Study design Prospective randomized experimental study. Animals Five experimental horses. Methods Five horses were anaesthetized twice (1week apart) in random order in lateral and in dorsal recumbency. Nine ventilation modes (treatments) were scheduled in random order (each lasting 4minutes) applying combinations of different tidal volumes (8, 10, 12mLkg-1) and positive end-expiratory pressures (PEEP) (0, 10, 20cm H2O). Baseline ventilation mode (tidal volume= 15mLkg-1, PEEP=0cm H2O) was applied for 4minutes between all treatments. Spirometry and RUP data were downloaded to personal computers. Linear regression analyses (RUP versus spirometric tidal volume) were performed using different subsets of data. Additonally RUP was calibrated against spirometry using a regression equation for all RUP signal values (thoracic, abdominal and combined) with all data collectively and also by an individually determined best regression equation (highest R2) for each experiment (horse versus recumbency) separately. Agreement between methods was assessed with Bland-Altman analyses. Results The highest correlation of RUP and spirometric tidal volume (R2=0.81) was found with the combined RUP signal in horses in lateral recumbency and ventilated without PEEP. The bias ±2 SD was 0±2.66L when RUP was calibrated for collective data, but decreased to 0±0.87L when RUP was calibrated with individual data. Conclusions and clinical relevance A possible use of RUP for tidal volume measurement during IPPV needs individual calibration to obtain limits of agreement within ±20%.

Original languageEnglish (US)
Pages (from-to)48-54
Number of pages7
JournalVeterinary Anaesthesia and Analgesia
Volume40
Issue number1
DOIs
StatePublished - Jan 2013
Externally publishedYes

Keywords

  • Anaesthesia
  • Horse
  • Mechanical ventilation
  • Monitoring
  • Respiratory ultrasonic plethysmography
  • Tidal volume

ASJC Scopus subject areas

  • veterinary(all)

Fingerprint Dive into the research topics of 'Measurement of tidal volume using Respiratory Ultrasonic Plethysmography in anaesthetized, mechanically ventilated horses'. Together they form a unique fingerprint.

  • Cite this