Measurement of multispectral scattering properties in mouse brain tissue

Eunjung Min, Sungbea Ban, Yanyan Wang, Sung Chul Bae, Gabriel Popescu, Catherine Best-Popescu, Woonggyu Jung

Research output: Contribution to journalArticlepeer-review


We present the scattering properties of mouse brain using multispectral diffraction phase microscopy. Typical diffraction phase microscopy was incorporated with the broadband light source which offers the measurement of the scattering coefficient and anisotropy in the spectral range of 550-900 nm. The regional analysis was performed for both the myeloarchitecture and cytoarchitecture of the brain tissue. Our results clearly evaluate the multispectral scattering properties in the olfactory bulb and corpus callosum. The scattering coefficient measured in the corpus callosum is about four times higher than in the olfactory bulb. It also indicates that it is feasible to realize the quantitative phase microscope in near infrared region for thick brain tissue imaging.

Original languageEnglish (US)
Article number#282487
Pages (from-to)1763-1770
Number of pages8
JournalBiomedical Optics Express
Issue number3
StatePublished - Mar 1 2017

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics


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